Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | S100A4 | P26447 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23168819 | 1.00 | ALDH1A1 (0.52) | ALDH1A1KMT2AMEN1KDM4ESMN1; SMN2 | |
| SCHEMBL18914677 | 0.87 | LGMN (0.53) | ALDH1A1KMT2AMEN1KDM4EHPGD | |
| SCHEMBL18914805 | 0.82 | ALDH1A1 (0.42) | ALDH1A1KMT2AMEN1KDM4ESMN1; SMN2 | |
| SCHEMBL23168999 | 0.82 | SHMT2 (0.43) | ALDH1A1KMT2AMEN1KDM4ESMN1; SMN2 | |
| SCHEMBL3436332 | 0.74 | ALDH1A1 (0.63) | ALDH1A1KMT2AMEN1KDM4ESMN1; SMN2 | |
| SCHEMBL1197272 | 0.74 | TSHR (0.56) | ALDH1A1KMT2AMEN1KDM4ESMN1; SMN2 | |
| SCHEMBL1197702 | 0.74 | TSHR (0.56) | ALDH1A1KMT2AMEN1KDM4ESMN1; SMN2 | |
| SCHEMBL23168880 | 0.73 | MAPT (0.58) | ALDH1A1KMT2AMEN1HPGDTSHR | |
| SCHEMBL3436239 | 0.72 | ALDH1A1 (0.56) | ALDH1A1KMT2AMEN1KDM4ESMN1; SMN2 | |
| SCHEMBL21848213 | 0.72 | SHMT2 (0.59) | ALDH1A1KMT2AKDM4ESMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017090743-A1 | NOVEL IMIDAZOLE COMPOUND AND USE THEREOF AS MELANOCORTIN RECEPTOR AGONIST | 田辺三菱製薬株式会社 | 2017-06-01 | — | — | WO | disclosed |