Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 7/20 | 0.46 |
| ▸ | LTB4R2 | Q9NPC1 | 6/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | HTR2B | P41595 | 1/20 | 0.45 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.42 |
| ▸ | TMEM97 | Q5BJF2 | 3/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23188908 | 0.86 | HTR2C (0.48) | HTR2CHTR2BL3MBTL1KDM4EMAPT | |
| SCHEMBL11919293 | 0.84 | L3MBTL1 (0.45) | LTB4RLTB4R2HTR2CHTR2BL3MBTL1 | |
| SCHEMBL12634447 | 0.84 | KCNH2 (0.44) | LTB4RLTB4R2HTR2CHTR2BNTRK1 | |
| SCHEMBL28043329 | 0.83 | L3MBTL1 (0.44) | LTB4RLTB4R2HTR2CHTR2BL3MBTL1 | |
| SCHEMBL18977773 | 0.83 | L3MBTL1 (0.51) | LTB4RLTB4R2L3MBTL1KDM4EMAPT | |
| SCHEMBL15417752 | 0.82 | L3MBTL1 (0.52) | L3MBTL1KDM4EMAPTNPSR1KCNH2 | |
| SCHEMBL9631985 | 0.81 | KCNH2 (0.54) | HTR2CHTR2BL3MBTL1MAPTKCNH2 | |
| SCHEMBL4311769 | 0.81 | HTR2C (0.55) | HTR2CHTR2BL3MBTL1MAPTKCNH2 | |
| SCHEMBL25475056 | 0.80 | MRGPRX4 (0.47) | LTB4RLTB4R2L3MBTL1KDM4EMAPT | |
| SCHEMBL12634522 | 0.80 | KCNH2 (0.48) | LTB4RLTB4R2HTR2CHTR2BNTRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3786167-A1 | DIARYL MACROCYCLIC COMPOUND AND PHARMACEUTICAL COMPOSITION, AND USE THEREOF | Primegene (Beijing) Co., Ltd. (CN) | 2021-03-03 | — | — | EP | disclosed |
| US-20190241582-A1 | Triazole ACC inhibitors and uses thereof | Nimbus Apollo, Inc. | 2019-08-08 | — | — | US | disclosed |
| WO-2017091600-A1 | PYRAZOLE ACC INHIBITORS AND USES THEREOF | GILEAD APOLLO, LLC (US) | 2017-06-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190241582-A1 | Triazole ACC inhibitors and uses thereof | ACACA, ACACB, ACAT1 | LTB4R 3374/4885LTB4R2 3481/4885HTR2C 4420/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.