SCHEMBL18915545

SCHEMBL18915545

c1ccc(-c2nc(-c3ccccc3)nc(-c3cccc(-c4cccc(-n5ncc6c7c(ccc65)[nH]c5ccc6ccc8ccccc8c6c57)c4)c3)n2)cc1

nearest known ligand 0.35

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CDK4 P11802 8/20 0.34
CCND1 P24385 8/20 0.34
NR3C1 P04150 1/20 0.33
PIK3CA P42336 3/20 0.32
MTOR P42345 3/20 0.32
KHK P50053 1/20 0.31
CCNB2 O95067 1/20 0.31
CCNE2 O96020 1/20 0.31
CDK1 P06493 1/20 0.31
CCNB1 P14635 1/20 0.31
CCNE1 P24864 1/20 0.31
CDK2 P24941 1/20 0.31
CCNB3 Q8WWL7 1/20 0.31
IRAK4 Q9NWZ3 1/20 0.31
GP6 Q9HCN6 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18915059 0.89 KHK (0.35) CDK4CCND1NR3C1KHKCCNB2
SCHEMBL20180183 0.84 NPC1 (0.40) NR3C1PIK3CAMTORKHKIRAK4
SCHEMBL20180181 0.79 NR3C1 (0.44) NR3C1PIK3CAMTORKHKIRAK4
SCHEMBL18915070 0.78 PIK3CA (0.34) NR3C1PIK3CAMTORKHK
SCHEMBL18915060 0.78 NR3C1 (0.36) NR3C1KHKIRAK4
SCHEMBL18915039 0.76 CDK4 (0.38) CDK4CCND1NR3C1KHKCCNB2
SCHEMBL18915062 0.76 RAB9A (0.39) CDK4CCND1KHK
SCHEMBL18915505 0.76 PIK3CA (0.35) NR3C1PIK3CAMTORKHK
SCHEMBL15811191 0.75 NR3C1 (0.39) NR3C1PIK3CAMTORKHK
SCHEMBL18914957 0.75 CDK4 (0.38) CDK4CCND1NR3C1KHKCCNB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2017090901-A1 ORGANIC LIGHT EMITTING COMPOUND AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME 주식회사 두산 2017-06-01 WO disclosed