Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 3/20 | 0.51 |
| ▸ | CYCS | P99999 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.46 |
| ▸ | STAT3 | P40763 | 1/20 | 0.45 |
| ▸ | STAT1 | P42224 | 1/20 | 0.45 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.43 |
| ▸ | TERT | O14746 | 2/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.43 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.43 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.43 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17651766 | 0.89 | TOP1 (0.41) | TOP1CYCSALDH1A1LMNAMAPT | |
| SCHEMBL17651795 | 0.89 | TOP1 (0.41) | TOP1CYCSALDH1A1LMNAMAPT | |
| SCHEMBL29831314 | 0.85 | PPARG (0.52) | CYCS | |
| SCHEMBL19718153 | 0.85 | PPARG (0.52) | CYCS | |
| SCHEMBL18917435 | 0.84 | STAT3 (0.47) | TOP1CYCSALDH1A1LMNAMAPT | |
| SCHEMBL29467148 | 0.84 | STAT3 (0.47) | TOP1CYCSALDH1A1LMNAMAPT | |
| SCHEMBL10523963 | 0.83 | TOP1 (0.60) | TOP1CYCSLMNAABCG2ENPP2 | |
| Acetic Acid SCHEMBL9639956 | 0.83 | TOP1 (0.67) | TOP1CYCSABCG2STAT3STAT1 | |
| SCHEMBL24221290 | 0.81 | ADORA2A (0.37) | TOP1CYCSALDH1A1LMNAMAPT | |
| SCHEMBL18917431 | 0.81 | TOP1 (0.51) | TOP1CYCSLMNAABCG2STAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108779124-B | Gold porphyrin-PEG conjugates and methods of use | 香港大学 | 2022-03-01 | — | — | CN | disclosed |
| US-11135310-B2 | Gold porphyrin-PEG conjugates and methods of use | THE UNIVERSITY OF HONG KONG (HK) | 2021-10-05 | — | — | US | disclosed |
| EP-3386986-B1 | GOLD PORPHYRIN-PEG CONJUGATES AND METHODS OF USE | UNIV HONG KONG (CN) | 2021-07-21 | — | — | EP | disclosed |
| US-20170157261-A1 | GOLD PORPHYRIN-PEG CONJUGATES AND METHODS OF USE | THE UNIVERSITY OF HONG KONG (HK) | 2017-06-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11135310-B2 | Gold porphyrin-PEG conjugates and methods of use | HCCS, PPOX, LIG3 | TOP1 715/4885CYCS 343/4885ALDH1A1 1068/4885 |
| US-20170157261-A1 | GOLD PORPHYRIN-PEG CONJUGATES AND METHODS OF USE | HCCS, PPOX, LIG3 | TOP1 715/4885CYCS 343/4885ALDH1A1 1068/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.