Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.52 |
| ▸ | PPARA | Q07869 | 1/20 | 0.52 |
| ▸ | PDE2A | O00408 | 2/20 | 0.43 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.43 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.43 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 5/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 5/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 5/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 5/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 5/20 | 0.42 |
| ▸ | DHFR | P00374 | 4/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19718153 | 1.00 | PPARG (0.52) | PPARGPPARAPDE2APDE3BPDE3A | |
| SCHEMBL29831938 | 0.88 | PPARG (0.51) | PPARGPPARAPDE2APDE3BPDE3A | |
| SCHEMBL19718136 | 0.88 | PPARG (0.51) | PPARGPPARAPDE2APDE3BPDE3A | |
| SCHEMBL18917432 | 0.85 | TOP1 (0.51) | CYCS | |
| SCHEMBL8908128 | 0.81 | PPARG (0.42) | PPARGPPARAHDAC3HDAC4HDAC1 | |
| SCHEMBL30293912 | 0.80 | HDAC1 (0.43) | PPARGPPARAPDE3BPDE3AP2RY12 | |
| SCHEMBL15399779 | 0.80 | TOP1 (0.49) | PPARGPPARAPDE2APDE3BPDE3A | |
| SCHEMBL7614765 | 0.80 | FABP4 (0.53) | PDE2APDE3BPDE3AP2RY12DHFR | |
| SCHEMBL8908441 | 0.80 | L3MBTL1 (0.50) | — | |
| SCHEMBL17651795 | 0.79 | TOP1 (0.41) | CYCS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109922834-B | Porphyrin compounds and compositions for the treatment of cancer | 良药治疗公司 | 2022-09-23 | — | — | CN | disclosed |