Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 1/20 | 0.47 |
| ▸ | STAT1 | P42224 | 1/20 | 0.47 |
| ▸ | TOP1 | P11387 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CYCS | P99999 | 4/20 | 0.39 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.37 |
| ▸ | GAPDH | P04406 | 2/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.34 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.34 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.34 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18917435 | 1.00 | STAT3 (0.47) | STAT3STAT1TOP1ALDH1A1LMNA | |
| SCHEMBL29467128 | 0.85 | GAPDH (0.39) | STAT3STAT1ALDH1A1LMNAMAPT | |
| SCHEMBL18917430 | 0.85 | GAPDH (0.39) | STAT3STAT1ALDH1A1LMNAMAPT | |
| SCHEMBL18917432 | 0.84 | TOP1 (0.51) | STAT3STAT1TOP1ALDH1A1LMNA | |
| SCHEMBL29467137 | 0.84 | CYCS (0.52) | STAT3STAT1TOP1ALDH1A1CYCS | |
| SCHEMBL18917440 | 0.84 | CYCS (0.52) | STAT3STAT1TOP1ALDH1A1CYCS | |
| SCHEMBL29904993 | 0.83 | STAT3 (0.62) | STAT3STAT1TOP1CYCSENPP2 | |
| SCHEMBL28024655 | 0.83 | STAT3 (0.62) | STAT3STAT1TOP1CYCSENPP2 | |
| SCHEMBL29467129 | 0.83 | STAT3 (0.54) | STAT3STAT1TOP1CYCSENPP2 | |
| SCHEMBL1640994 | 0.83 | STAT3 (0.54) | STAT3STAT1TOP1CYCSENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108779124-B | Gold porphyrin-PEG conjugates and methods of use | 香港大学 | 2022-03-01 | — | — | CN | disclosed |