Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | NPC1 | O15118 | 4/20 | 0.37 |
| ▸ | RAB9A | P51151 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | PTPRC | P08575 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | BLM | P54132 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18917445 | 0.82 | CYP3A4 (0.37) | CYP3A4NFKB1PMP22CYP2D6ALDH1A1 | |
| SCHEMBL18917449 | 0.78 | ANPEP (0.44) | CYP3A4NFKB1PMP22CYP2D6ALDH1A1 | |
| SCHEMBL14011320 | 0.63 | RXFP1 (0.47) | CYP3A4NFKB1PMP22ALDH1A1SMN1; SMN2 | |
| SCHEMBL14011318 | 0.63 | KMT2A (0.50) | CYP3A4NFKB1PMP22ALDH1A1NPC1 | |
| SCHEMBL17813341 | 0.62 | PRKCI (0.42) | CYP3A4ALDH1A1TSHRMAPK1TDP1 | |
| SCHEMBL6572103 | 0.62 | MEN1 (0.38) | CYP3A4ALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6574447 | 0.62 | ALDH1A1 (0.41) | CYP3A4ALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL27637718 | 0.62 | ANPEP (0.46) | CYP3A4NFKB1PMP22CYP2D6ALDH1A1 | |
| SCHEMBL6687632 | 0.60 | RXFP1 (0.71) | CYP3A4ALDH1A1RAB9ATSHRTDP1 | |
| SCHEMBL20979820 | 0.60 | CASP3 (0.50) | ALDH1A1NPC1RAB9ASMN1; SMN2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170158608-A1 | Process for the Preparation of 2-Alkoxymethyl-1,4-Benzenediamines | THE PROCTER & GAMBLE COMPANY | 2017-06-08 | — | — | US | disclosed |
| WO-2017095677-A1 | PROCESS FOR THE PREPARATION OF 2-ALKOXYMETHYL-1, 4-BENZENEDIAMINES | THE PROCTER & GAMBLE COMPANY (US) | 2017-06-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170158608-A1 | Process for the Preparation of 2-Alkoxymethyl-1,4-Benzenediamines | CYP1A1, CYP4B1, CYP1B1 | CYP3A4 5/4885NFKB1 3077/4885PMP22 1692/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.