Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 2/20 | 0.44 |
| ▸ | DPP4 | P27487 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.41 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | CASP1 | P29466 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18917442 | 0.78 | CYP3A4 (0.39) | ANPEPDPP4CYP3A4NFKB1PMP22 | |
| SCHEMBL18917445 | 0.77 | CYP3A4 (0.37) | ANPEPDPP4CYP3A4NFKB1PMP22 | |
| SCHEMBL10885032 | 0.72 | CYP3A4 (0.66) | ANPEPDPP4CYP3A4NFKB1PMP22 | |
| SCHEMBL18806460 | 0.69 | CYP3A4 (0.61) | ANPEPDPP4CYP3A4NFKB1PMP22 | |
| SCHEMBL30136662 | 0.69 | TGM2 (0.49) | ANPEPDPP4CYP3A4NFKB1PMP22 | |
| SCHEMBL11824560 | 0.66 | ALDH1A1 (0.50) | CYP3A4ALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL28266745 | 0.66 | ALDH1A1 (0.52) | ANPEPDPP4CYP3A4NFKB1PMP22 | |
| SCHEMBL14011318 | 0.66 | KMT2A (0.50) | ANPEPDPP4CYP3A4NFKB1PMP22 | |
| SCHEMBL8146041 | 0.66 | ALDH1A1 (0.54) | ANPEPDPP4CYP3A4ALDH1A1NPC1 | |
| SCHEMBL214484 | 0.66 | ALDH1A1 (0.54) | CYP3A4ALDH1A1TSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170158608-A1 | Process for the Preparation of 2-Alkoxymethyl-1,4-Benzenediamines | THE PROCTER & GAMBLE COMPANY | 2017-06-08 | — | — | US | disclosed |
| WO-2017095677-A1 | PROCESS FOR THE PREPARATION OF 2-ALKOXYMETHYL-1, 4-BENZENEDIAMINES | THE PROCTER & GAMBLE COMPANY (US) | 2017-06-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170158608-A1 | Process for the Preparation of 2-Alkoxymethyl-1,4-Benzenediamines | CYP1A1, CYP4B1, CYP1B1 | ANPEP 3261/4885DPP4 2999/4885CYP3A4 5/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.