Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | PBK | Q96KB5 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | LTA4H | P09960 | 2/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13694086 | 0.97 | POLB (0.53) | POLBEPHX2NPC1RAB9APBK | |
| SCHEMBL1803149 | 0.83 | NPC1 (0.46) | POLBNPC1RAB9APBKPARP1 | |
| SCHEMBL28133185 | 0.82 | ALDH1A1 (0.46) | EPHX2RAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL28351994 | 0.81 | ALDH1A1 (0.54) | POLBALDH1A1MEN1KMT2ALTA4H | |
| SCHEMBL21041192 | 0.81 | ALDH1A1 (0.54) | POLBALDH1A1MEN1KMT2ALTA4H | |
| SCHEMBL3760743 | 0.81 | ADRB1 (0.59) | POLBPBKPARP1HPGD | |
| SCHEMBL6221703 | 0.81 | ADRB1 (0.59) | POLBPBKPARP1HPGD | |
| SCHEMBL8396806 | 0.80 | NPC1 (0.70) | EPHX2NPC1RAB9AALDH1A1MEN1 | |
| SCHEMBL8393668 | 0.79 | NPC1 (0.73) | EPHX2NPC1RAB9AALDH1A1MEN1 | |
| SCHEMBL8395990 | 0.79 | NPC1 (0.73) | EPHX2NPC1RAB9AALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3160517-B1 | WATER-SOLUBLE ACTIVATABLE MOLECULAR PROBES, INTERMEDIATES FOR THE SYNTHESIS THEREOF AND ASSOCIATED DETECTION METHODS | ECOLE NORMALE SUPERIEURE LYON (FR) | 2024-06-12 | — | — | EP | disclosed |
| CN-106470977-B | Water-soluble activatable molecular probe, synthetic intermediate thereof and related detection method | 里昂高等师范学院 | 2021-07-09 | — | — | CN | disclosed |
| US-10179929-B2 | Water-soluble activatable molecular probes, intermediates for the synthesis thereof and associated detection methods | ECOLE NORMALE SUPERIEURE DE LYON (FR) | 2019-01-15 | — | — | US | disclosed |
| US-10179929-B2 | Water-soluble activatable molecular probes, intermediates for the synthesis thereof and associated detection methods | ECOLE NORMALE SUPERIEURE DE LYON (FR) | 2019-01-15 | — | — | US | disclosed |
| US-20170159100-A1 | WATER-SOLUBLE ACTIVATABLE MOLECULAR PROBES, INTERMEDIATES FOR THE SYNTHESIS THEREOF AND ASSOCIATED DETECTION METHODS | ECOLE NORMALE SUPERIEURE DE LYON (FR) | 2017-06-08 | — | — | US | disclosed |
| US-20170159100-A1 | WATER-SOLUBLE ACTIVATABLE MOLECULAR PROBES, INTERMEDIATES FOR THE SYNTHESIS THEREOF AND ASSOCIATED DETECTION METHODS | ECOLE NORMALE SUPERIEURE DE LYON (FR) | 2017-06-08 | — | — | US | disclosed |
| CN-106470977-A | Water solublity can anakmetomeres probe, its synthetic intermediate and related detecting method | 里昂高等师范学院 | 2017-03-01 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10179929-B2 | Water-soluble activatable molecular probes, intermediates for the synthesis thereof and associated detection methods | SI, GUSB, ABCG2 | POLB 559/4885EPHX2 32/4885NPC1 2451/4885 |
| US-20170159100-A1 | WATER-SOLUBLE ACTIVATABLE MOLECULAR PROBES, INTERMEDIATES FOR THE SYNTHESIS THEREOF AND ASSOCIATED DETECTION METHODS | SI, GUSB, ABCG2 | POLB 559/4885EPHX2 32/4885NPC1 2451/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.