SCHEMBL18917586

SCHEMBL18917586

CCCCOc1cccc(C(=O)c2ccccc2)c1

nearest known ligand 0.77

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.69
MAPK1 P28482 1/20 0.69
L3MBTL1 Q9Y468 1/20 0.69
KMT2A Q03164 1/20 0.65
PLA2G4B P0C869 2/20 0.63
NR1H4 Q96RI1 2/20 0.60
KAT6A Q92794 1/20 0.60
SMPD1 P17405 3/20 0.59
HRH3 Q9Y5N1 1/20 0.59
THRB P10828 2/20 0.58
SRD5A2 P31213 1/20 0.57
GAA P10253 1/20 0.55
PPARA Q07869 1/20 0.55
THRA P10827 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13236857 0.95 KMT2A (0.68) LMNAMAPK1L3MBTL1KMT2APLA2G4B
SCHEMBL11696519 0.92 KMT2A (0.77) LMNAMAPK1L3MBTL1KMT2APLA2G4B
SCHEMBL6657609 0.88 LMNA (0.59) LMNAMAPK1L3MBTL1KMT2APLA2G4B
SCHEMBL12442559 0.88 SMPD1 (0.61) LMNAMAPK1L3MBTL1KMT2APLA2G4B
SCHEMBL3315904 0.87 KMT2A (0.84) KMT2APLA2G4BNR1H4SMPD1
SCHEMBL50280 0.87 GAA (0.72) LMNAMAPK1L3MBTL1PLA2G4BGAA
SCHEMBL27913517 0.87 KMT2A (0.78) LMNAMAPK1L3MBTL1KMT2APLA2G4B
SCHEMBL11504437 0.87 KMT2A (0.56) LMNAMAPK1L3MBTL1KMT2APLA2G4B
SCHEMBL18917584 0.85 L3MBTL1 (0.75) LMNAMAPK1L3MBTL1KMT2ANR1H4
SCHEMBL8414531 0.84 KMT2A (0.65) LMNAMAPK1L3MBTL1KMT2APLA2G4B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106715479-B Catalyst for polymerization of conjugated diene, conjugated diene polymer, modified conjugated diene polymer, polybutadiene, and composition containing same 宇部兴产株式会社 2019-07-23 CN disclosed
US-10053526-B2 Catalyst for conjugated diene polymerization, conjugated diene polymer, modified conjugated diene polymer, polybutadiene, and compositions comprising foregoing UBE INDUSTRIES, LTD. (JP) 2018-08-21 US disclosed
US-20170158786-A1 CATALYST FOR CONJUGATED DIENE POLYMERIZATION, CONJUGATED DIENE POLYMER, MODIFIED CONJUGATED DIENE POLYMER, POLYBUTADIENE, AND COMPOSITIONS COMPRISING FOREGOING UBE INDUSTRIES, LTD. (JP) 2017-06-08 US disclosed
CN-106715479-A Catalyst for polymerization of conjugated diene, conjugated diene polymer, modified conjugated diene polymer, polybutadiene, and composition containing same 宇部兴产株式会社 2017-05-24 CN disclosed