Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 12/20 | 0.53 |
| ▸ | MAOB | P27338 | 12/20 | 0.53 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.53 |
| ▸ | PRKCI | P41743 | 1/20 | 0.47 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.42 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | CDC25B | P30305 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1380751 | 0.88 | CASP1 (0.44) | MAOAMAOBCYP2A6PRKCIHSD17B1 | |
| SCHEMBL1452496 | 0.84 | MAOA (0.53) | MAOAMAOBCYP2A6PRKCIHSD17B1 | |
| SCHEMBL7112522 | 0.82 | MAOA (0.35) | MAOAMAOBCYP2A6PRKCIHSD17B1 | |
| SCHEMBL1385848 | 0.80 | MAOA (0.48) | MAOAMAOBCYP2A6PRKCIHSD17B1 | |
| SCHEMBL22367713 | 0.77 | — | — | |
| SCHEMBL134194 | 0.75 | — | — | |
| SCHEMBL12496250 | 0.74 | PARP10 (0.44) | GRM5 | |
| SCHEMBL23277084 | 0.74 | PBRM1 (0.33) | MAOAMAOBCYP2A6 | |
| SCHEMBL23306 | 0.73 | — | — | |
| SCHEMBL29193390 | 0.72 | TSHR (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 136 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE47451-E1 | Thieno[3,2-D]pyrimidine derivatives having inhibitory activity for protein kinases | HANMI PHARM. CO. LTD. (KR) | 2019-06-25 | — | — | US | claimed |
| US-9156852-B2 | Thieno[3,2-D]pyrimidine derivatives having inhibitory activity for protein kinases | HANMI PHARM. CO., LTD (KR) | 2015-10-13 | — | — | US | claimed |
| EP-0817772-B1 | PYRROLIDINYL HYDROXAMIC ACID COMPOUNDS AND THEIR PRODUCTION PROCESS | PFIZER (US) | 2003-01-29 | — | — | EP | claimed |
| EP-0789021-B1 | Hydroxamic acid compounds as opioid kappa receptor agonists | PFIZER (US) | 2000-10-11 | — | — | EP | claimed |
| US-6004964-A | ADMINISTERING AMIDE OR SULFONAMIDE DERIVATIVE; ANALGESICS | ADOLOR CORPORATION (US) | 1999-12-21 | — | — | US | claimed |
| US-5952369-A | ANALGESIC, TREATMENT FOR STROKE OR ABDOMINAL PAIN ASSOCIATED WITH FUNCTIONAL BOWEL DISEASE | PFIZER INC (US) | 1999-09-14 | — | — | US | claimed |
| US-5837717-A | ANALGESICS, ANTIINFLAMMATORY AGENTS, ANTITUSSIVE AGENTS, DIURETICS, NEUROPROTECTIVE AGENTS; TREATING BOWEL DISEASE SUCH AS ABDOMINAL PAIN | PFIZER INC. (US) | 1998-11-17 | — | — | US | claimed |
| EP-0817772-A1 | PYRROLIDINYL HYDROXAMIC ACID COMPOUNDS AND THEIR PRODUCTION PROCESS | PFIZER INC. (US) | 1998-01-14 | — | — | EP | claimed |
| EP-0789021-A1 | Hydroxamic acid compounds as opioid kappa receptor agonists | PFIZER INC. (US) | 1997-08-13 | — | — | EP | claimed |
| WO-1996030339-A1 | PYRROLIDINYL HYDROXAMIC ACID COMPOUNDS AND THEIR PRODUCTION PROCESS | PFIZER INC. (US) | 1996-10-03 | — | — | WO | claimed |
| EP-4373890-A1 | DIBENZOXANTHENE QUENCHERS, USES, AND METHODS OF PREPARATION | Life Technologies Corporation (US) | 2024-05-29 | — | — | EP | disclosed |
| CN-117897454-A | Dibenzoxanthene quencher, use and preparation method | 生命技术公司 | 2024-04-16 | — | — | CN | disclosed |
| US-20240110063-A1 | DIBENZOXANTHENE QUENCHERS, USES, AND METHODS OF PREPARATION | Life Technologies Corporation | 2024-04-04 | — | — | US | disclosed |
| WO-2023004400-A1 | DIBENZOXANTHENE QUENCHERS, USES, AND METHODS OF PREPARATION | Life Technologies Corporation (US) | 2023-01-26 | — | — | WO | disclosed |
| EP-3209794-A1 | MODULATING ADIPOSE TISSUE AND ADIPOGENESIS | Katholieke Universiteit Leuven KU Leuven Research & Development (BE) | 2017-08-30 | — | — | EP | disclosed |
| EP-0368670-A1 | Trisubstituted piperazine compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1990-05-16 | — | — | EP | disclosed |
| US-4906773-A | Process for preparing optically active threonine | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1990-03-06 | — | — | US | disclosed |
| US-4880809-A | HYPOTENSIVE AGENTS, AMIDE DERIVATIVES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1989-11-14 | — | — | US | disclosed |
| EP-0322236-A2 | Catalytic process for preparing optically active threonine | Takasago International Corporation (JP) | 1989-06-28 | — | — | EP | disclosed |
| EP-0284359-A1 | 1,4-Disubstituted piperazine compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1988-09-28 | — | — | EP | disclosed |