⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7915914 | 0.67 | — | — | |
| SCHEMBL14396181 | 0.67 | — | — | |
| SCHEMBL24445848 | 0.64 | — | — | |
| SCHEMBL1770288 | 0.64 | — | — | |
| SCHEMBL1813630 | 0.64 | THRB (0.38) | — | |
| SCHEMBL344 | 0.61 | CA2 (0.41) | — | |
| SCHEMBL27892503 | 0.61 | CA2 (0.41) | — | |
| Bicarbonate SCHEMBL28136957 | 0.61 | CA2 (0.50) | — | |
| SCHEMBL22352884 | 0.59 | ACLY (0.31) | — | |
| SCHEMBL20680198 | 0.59 | THRB (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3181576-B1 | METHOD FOR SYNTHESIZING 25-HYDROXY CHOLESTEROL | UNIV ZHEJIANG TECHNOLOGY (CN) | 2019-09-04 | — | — | EP | disclosed |
| US-9802977-B2 | Method of synthesizing 25-hydroxy cholesterol | ZHEJIANG UNIVERSITY OF TECHNOLOGY (CN) | 2017-10-31 | — | — | US | disclosed |
| EP-3181576-A1 | METHOD FOR SYNTHESIZING 25-HYDROXY CHOLESTEROL | Zhejiang University of Technology (CN) | 2017-06-21 | — | — | EP | disclosed |
| US-20170158729-A1 | METHOD OF SYNTHESIZING 25-HYDROXY CHOLESTEROL | ZHEJIANG UNIVERSITY OF TECHNOLOGY (CN) | 2017-06-08 | — | — | US | disclosed |