Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RGS4 | P49798 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 5/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 5/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 5/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.36 |
| ▸ | HDAC9 | Q9UKV0 | 5/20 | 0.36 |
| ▸ | HDAC5 | Q9UQL6 | 5/20 | 0.36 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 4/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20574598 | 0.82 | RGS4 (0.41) | RGS4 | |
| SCHEMBL18919435 | 0.79 | PTGS1 (0.49) | — | |
| SCHEMBL4855647 | 0.74 | RGS4 (0.41) | RGS4SIRT1 | |
| SCHEMBL15433041 | 0.73 | PTGS1 (0.57) | RGS4HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL4852749 | 0.72 | PTGS1 (0.60) | RGS4HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL4846116 | 0.72 | PTGS1 (0.60) | RGS4HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL20574477 | 0.71 | RGS4 (0.50) | RGS4SIRT1 | |
| SCHEMBL18925542 | 0.70 | RGS4 (0.42) | RGS4HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL18919457 | 0.69 | ACHE (0.39) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL20210376 | 0.69 | PTGS1 (0.44) | RGS4HDAC3HDAC4HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3383846-A1 | CARBON MONOXIDE RELEASING NORBORNENONE COMPOUNDS | Sammut, Ivan Andrew (NZ) | 2018-10-10 | — | — | EP | disclosed |
| WO-2017095237-A1 | CARBON MONOXIDE RELEASING NORBORNENONE COMPOUNDS | SAMMUT IVAN ANDREW (NZ) | 2017-06-08 | — | — | WO | disclosed |