Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.53 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | SCN4A | P35499 | 1/20 | 0.44 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | F10 | P00742 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28004758 | 0.86 | ALDH1A1 (0.50) | MEN1KMT2AALDH1A1TSHRMAPT | |
| SCHEMBL2211636 | 0.73 | ALDH1A1 (0.53) | MEN1KMT2AALDH1A1TSHRMAPT | |
| SCHEMBL5963048 | 0.72 | SCN9A (0.54) | SMN1; SMN2MEN1KMT2ASCN9APARP10 | |
| SCHEMBL2002688 | 0.71 | ALDH1A1 (0.73) | SMN1; SMN2MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL2204639 | 0.70 | ALDH1A1 (0.55) | MEN1KMT2AALDH1A1TSHRMAPT | |
| SCHEMBL9988378 | 0.69 | SCN9A (1.00) | KMT2ASCN9APARP10MAPTSCN4A | |
| SCHEMBL15569357 | 0.69 | LMNA (0.42) | SMN1; SMN2MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL11606815 | 0.69 | FLT3 (0.49) | SMN1; SMN2ALDH1A1TSHRMAPTMAPK1 | |
| SCHEMBL9565147 | 0.69 | PKM (0.56) | SMN1; SMN2MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL22163779 | 0.69 | SRD5A2 (0.51) | SMN1; SMN2MEN1KMT2APARP10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017093351-A1 | CPLA2 INHIBITORS | Westfälische Wilhelms-Universität Münster (DE) | 2017-06-08 | — | — | WO | disclosed |