Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 8/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | RECQL | P46063 | 2/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | MGAM | O43451 | 1/20 | 0.40 |
| ▸ | SI | P14410 | 1/20 | 0.40 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | G6PD | P11413 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17431233 | 0.87 | KDM4E (0.33) | GAAKDM4EMAPTALDH1A1RECQL | |
| SCHEMBL16024771 | 0.86 | NPC1 (0.46) | GAAKDM4EMAPTALDH1A1MEN1 | |
| SCHEMBL8440252 | 0.76 | NPC1 (0.61) | GAAKDM4EMAPTALDH1A1MEN1 | |
| SCHEMBL29763172 | 0.76 | NPC1 (0.61) | GAAKDM4EMAPTALDH1A1MEN1 | |
| SCHEMBL18924725 | 0.72 | MAOB (0.58) | GAAKDM4EMAPTALDH1A1MEN1 | |
| SCHEMBL29083062 | 0.70 | GAA (0.52) | GAAKDM4EMAPTALDH1A1MEN1 | |
| SCHEMBL11616701 | 0.69 | NPC1 (0.54) | GAAKDM4EMAPTALDH1A1MEN1 | |
| Hydrochloric Acid SCHEMBL6781089 | 0.69 | ALDH1A1 (0.53) | GAAKDM4EMAPTALDH1A1MEN1 | |
| SCHEMBL9068308 | 0.68 | NPC1 (0.53) | GAAKDM4EMAPTALDH1A1MEN1 | |
| SCHEMBL6575715 | 0.67 | PDE10A (0.52) | GAAKDM4EMAPTALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9670108-B2 | Bisphosphites having a central 2,3′-biphenol unit | EVONIK DEGUSSA GMBH (DE) | 2017-06-06 | — | — | US | disclosed |