Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | MEN1 | O00255 | 4/20 | 0.59 |
| ▸ | MAPT | P10636 | 4/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | GAA | P10253 | 4/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | THRB | P10828 | 1/20 | 0.59 |
| ▸ | RECQL | P46063 | 1/20 | 0.59 |
| ▸ | BLM | P54132 | 1/20 | 0.59 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | ERN1 | O75460 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | APP | P05067 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29763172 | 1.00 | NPC1 (0.61) | NPC1ALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL11616701 | 0.91 | NPC1 (0.54) | NPC1ALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL9068308 | 0.89 | NPC1 (0.53) | NPC1ALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL29541984 | 0.87 | KMT2A (0.61) | NPC1ALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL29083062 | 0.84 | GAA (0.52) | NPC1ALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL9638313 | 0.83 | MAPT (0.60) | NPC1MEN1MAPTKMT2AGAA | |
| SCHEMBL17274611 | 0.83 | NPC1 (0.47) | NPC1ALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL27613014 | 0.83 | ALDH1A1 (0.55) | NPC1ALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL8940685 | 0.83 | ALDH1A1 (0.55) | NPC1ALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL67498 | 0.82 | ALDH1A1 (0.61) | NPC1ALDH1A1MEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104053663-B | Process for purifying organodiphosphite compounds | 巴斯夫欧洲公司 | 2017-07-04 | — | — | CN | claimed |
| US-10759997-B2 | Polymerizable compound, liquid crystal medium containing same and liquid crystal display device | SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIAL CO., LTD. (CN) | 2020-09-01 | — | — | US | disclosed |
| CN-104053663-B | Process for purifying organodiphosphite compounds | 巴斯夫欧洲公司 | 2017-07-04 | — | — | CN | disclosed |
| CN-104837853-B | Bisphosphite mixture and use thereof as catalyst mixture in hydroformylation | 赢创德固赛有限公司 | 2017-05-10 | — | — | CN | disclosed |
| EP-0757672-B1 | MONODENTATE PHOSPHITE AND NICKEL CATALYST COMPOSITION FOR MONOOLEFIN HYDROCYANATION | DU PONT (US) | 1999-06-16 | — | — | EP | disclosed |
| EP-0757672-A1 | MONODENTATE PHOSPHITE AND NICKEL CATALYST COMPOSITION FOR MONOOLEFIN HYDROCYANATION | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1997-02-12 | — | — | EP | disclosed |
| EP-0590613-B1 | Improved hydroformylation process | UNION CARBIDE CHEM PLASTIC (US) | 1997-01-08 | — | — | EP | disclosed |
| US-5543536-A | Monodentate phosphite and nickel catalyst composition for monoolefin hydrocyanation | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1996-08-06 | — | — | US | disclosed |
| US-5512696-A | HYDROCYANATION OF ALIPHATIC MONOETHYLENICALLY UNSATURATEDCOMPOUND | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1996-04-30 | — | — | US | disclosed |
| WO-1995029153-A1 | MONODENTATE PHOSPHITE AND NICKEL CATALYST COMPOSITION FOR MONOOLEFIN HYDROCYANATION | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1995-11-02 | — | — | WO | disclosed |
| EP-0590613-A2 | Improved hydroformylation process | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1994-04-06 | — | — | EP | disclosed |
| US-5288918-A | Using a rhodium-organobisphosphite complex catalyst | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1994-02-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10759997-B2 | Polymerizable compound, liquid crystal medium containing same and liquid crystal display device | BPHL, KLK3, NEFM | NPC1 4521/4885ALDH1A1 2237/4885MEN1 1931/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.