Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 6/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | RECQL | P46063 | 2/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | G6PD | P11413 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | MGAM | O43451 | 1/20 | 0.44 |
| ▸ | SI | P14410 | 1/20 | 0.44 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18922917 | 0.86 | GAA (0.41) | NPC1GAAKDM4EMAPTRECQL | |
| SCHEMBL18924725 | 0.85 | MAOB (0.58) | GAAKDM4EMAPTRECQLMCL1 | |
| SCHEMBL8440252 | 0.82 | NPC1 (0.61) | NPC1GAAKDM4EMAPTRECQL | |
| SCHEMBL29763172 | 0.82 | NPC1 (0.61) | NPC1GAAKDM4EMAPTRECQL | |
| SCHEMBL29083062 | 0.76 | GAA (0.52) | NPC1GAAKDM4EMAPTRECQL | |
| SCHEMBL595280 | 0.76 | MAOB (0.64) | NFE2L2GAAKDM4EMAPTRECQL | |
| SCHEMBL27613014 | 0.75 | ALDH1A1 (0.55) | NPC1GAAKDM4EMAPTRECQL | |
| SCHEMBL8940685 | 0.75 | ALDH1A1 (0.55) | NPC1GAAKDM4EMAPTRECQL | |
| SCHEMBL11616701 | 0.74 | NPC1 (0.54) | NPC1GAAKDM4EMAPTRECQL | |
| SCHEMBL17293919 | 0.74 | CA2 (0.56) | GAAKDM4EMAPTRECQLMCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3029044-B1 | BIS-PHOSPHITES WITH AN ASYMMETRIC BIARYL CENTRAL COMPONENT | EVONIK DEGUSSA GMBH (DE) | 2019-05-01 | — | — | EP | disclosed |
| EP-3029057-B1 | BIS-PHOSPHITES WITH AN ASYMMETRIC BIARYL CENTRAL COMPONENT | EVONIK DEGUSSA GMBH (DE) | 2019-02-20 | — | — | EP | disclosed |
| EP-3029056-B1 | BIS-PHOSPHITES WITH AN ASYMMETRIC BIARYL CENTRAL COMPONENT | EVONIK DEGUSSA GMBH (DE) | 2018-11-07 | — | — | EP | disclosed |
| EP-3029045-B1 | Bis-phosphites with 2.3 -biphenol unit as central component | EVONIK DEGUSSA GMBH (DE) | 2018-06-13 | — | — | EP | disclosed |
| US-9982001-B2 | Bisphosphites having an unsymmetric central biaryl unit | EVONIK DEGUSSA GMBH (DE) | 2018-05-29 | — | — | US | disclosed |
| US-9879353-B2 | Electrochemical coupling of two phenols which differ in their oxidation potential | EVONIK DEGUSSA GMBH (DE) | 2018-01-30 | — | — | US | disclosed |
| US-9879353-B2 | Electrochemical coupling of two phenols which differ in their oxidation potential | EVONIK DEGUSSA GMBH (DE) | 2018-01-30 | — | — | US | disclosed |
| US-9879353-B2 | Electrochemical coupling of two phenols which differ in their oxidation potential | EVONIK DEGUSSA GMBH (DE) | 2018-01-30 | — | — | US | disclosed |
| US-9670108-B2 | Bisphosphites having a central 2,3′-biphenol unit | EVONIK DEGUSSA GMBH (DE) | 2017-06-06 | — | — | US | disclosed |
| US-9670108-B2 | Bisphosphites having a central 2,3′-biphenol unit | EVONIK DEGUSSA GMBH (DE) | 2017-06-06 | — | — | US | disclosed |
| EP-3029057-A1 | BIS-PHOSPHITES WITH AN ASYMMETRIC BIARYL CENTRAL COMPONENT | Evonik Degussa GmbH (DE) | 2016-06-08 | — | — | EP | disclosed |
| EP-3029056-A1 | BIS-PHOSPHITES WITH AN ASYMMETRIC BIARYL CENTRAL COMPONENT | Evonik Degussa GmbH (DE) | 2016-06-08 | — | — | EP | disclosed |
| EP-3029051-A1 | Bis-phosphites with a naphthyl-phenyl unit as fin component and a 2.3'-bisphenol unit as central component | Evonik Degussa GmbH (DE) | 2016-06-08 | — | — | EP | disclosed |
| EP-3029044-A1 | Bis-phosphites with an asymmetric biaryl central component | Evonik Degussa GmbH (DE) | 2016-06-08 | — | — | EP | disclosed |
| EP-3029045-A1 | Bis-phosphites with 2.3 -biphenol unit as central component | Evonik Degussa GmbH (DE) | 2016-06-08 | — | — | EP | disclosed |
| EP-3029058-A1 | BIS-PHOSPHITES WITH AN ASYMMETRIC BIARYL CENTRAL COMPONENT | Evonik Degussa GmbH (DE) | 2016-06-08 | — | — | EP | disclosed |
| US-20160010225-A1 | ELECTROCHEMICAL COUPLING OF TWO PHENOLS WHICH DIFFER IN THEIR OXIDATION POTENTIAL | EVONIK DEGUSSA GMBH (DE) | 2016-01-14 | — | — | US | disclosed |
| US-20160010225-A1 | ELECTROCHEMICAL COUPLING OF TWO PHENOLS WHICH DIFFER IN THEIR OXIDATION POTENTIAL | EVONIK DEGUSSA GMBH (DE) | 2016-01-14 | — | — | US | disclosed |
| US-20160010225-A1 | ELECTROCHEMICAL COUPLING OF TWO PHENOLS WHICH DIFFER IN THEIR OXIDATION POTENTIAL | EVONIK DEGUSSA GMBH (DE) | 2016-01-14 | — | — | US | disclosed |
| WO-2014135236-A1 | ELECTROCHEMICAL COUPLING OF TWO PHENOLS WHICH DIFFER IN THEIR OXIDATION POTENTIAL | EVONIK INDUSTRIES AG (DE) | 2014-09-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160010225-A1 | ELECTROCHEMICAL COUPLING OF TWO PHENOLS WHICH DIFFER IN THEIR OXIDATION POTENTIAL | COMT, MT-CO2, CYP11B2 | NPC1 4741/4885NFE2L2 34/4885GAA 2519/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.