SCHEMBL18922928

SCHEMBL18922928

O=C(OC(F)(F)C(F)(F)C(F)(F)C(=O)O)C1CC2CCC1C2

nearest known ligand 0.37

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.35
HPGD P15428 1/20 0.33
KCNQ3 O43525 1/20 0.33
KCNQ2 O43526 1/20 0.33
KCNQ4 P56696 1/20 0.33
KCNQ5 Q9NR82 1/20 0.33
HSD11B1 P28845 1/20 0.32
ATM Q13315 1/20 0.31
THRB P10828 2/20 0.31
MEN1 O00255 1/20 0.30
HTT P42858 1/20 0.30
KMT2A Q03164 1/20 0.30
GAA P10253 1/20 0.30
SLC6A3 Q01959 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18467938 0.91 POLB (0.39) POLBL3MBTL1HPGDKCNQ3KCNQ2
SCHEMBL2632930 0.81 POLB (0.41) POLBL3MBTL1HPGDKCNQ3KCNQ2
SCHEMBL25889181 0.77 POLB (0.37) POLBL3MBTL1HPGDKCNQ3KCNQ2
SCHEMBL17955662 0.76 HSD11B1 (0.32) POLBHSD11B1
SCHEMBL26190807 0.75 POLB (0.36) POLBL3MBTL1HPGDKCNQ3KCNQ2
SCHEMBL22043918 0.75 HSD11B1 (0.32) POLBHSD11B1
SCHEMBL26190677 0.73 POLB (0.35) POLBL3MBTL1KCNQ3KCNQ2KCNQ4
SCHEMBL7647666 0.73 POLB (0.52) POLBL3MBTL1HPGDKCNQ3KCNQ2
SCHEMBL7647668 0.73 POLB (0.52) POLBL3MBTL1HPGDKCNQ3KCNQ2
SCHEMBL85684 0.73 POLB (0.44) POLBL3MBTL1HPGDKCNQ3KCNQ2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9671693-B2 Resist composition and method for producing resist pattern SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-06-06 US disclosed