SCHEMBL85684

SCHEMBL85684

CC(C)(C)OC(=O)C1CC2CCC1C2

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.44
KCNQ3 O43525 1/20 0.42
KCNQ2 O43526 1/20 0.42
KCNQ4 P56696 1/20 0.42
KCNQ5 Q9NR82 1/20 0.42
HSD11B1 P28845 1/20 0.41
L3MBTL1 Q9Y468 2/20 0.38
NPC1 O15118 3/20 0.37
RAB9A P51151 3/20 0.37
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
HPGD P15428 2/20 0.36
HSD17B10 Q99714 1/20 0.36
ALDH1A1 P00352 1/20 0.36
MAPT P10636 1/20 0.36
MAPK1 P28482 1/20 0.36
GFER P55789 1/20 0.36
TSHR P16473 1/20 0.36
BRS3 P32247 1/20 0.35
CHRM2 P08172 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13668773 1.00 POLB (0.44) POLBKCNQ3KCNQ2KCNQ4KCNQ5
SCHEMBL5158350 0.91 CHRM2 (0.36) POLBKCNQ3KCNQ2KCNQ4KCNQ5
SCHEMBL1105067 0.83 POLB (0.44) POLBKCNQ3KCNQ2KCNQ4KCNQ5
SCHEMBL32688683 0.82 POLB (0.41) POLBKCNQ3KCNQ2KCNQ4KCNQ5
SCHEMBL9908349 0.80 POLB (0.41) POLBKCNQ3KCNQ2KCNQ4KCNQ5
SCHEMBL14905911 0.80 POLB (0.38) POLBKCNQ3KCNQ2KCNQ4KCNQ5
SCHEMBL17070174 0.80 POLB (0.38) POLBKCNQ3KCNQ2KCNQ4KCNQ5
SCHEMBL3195516 0.80 PREP (0.40) MEN1KMT2AHPGDMAPK1CHRM2
SCHEMBL18435822 0.80 MAPK1 (0.35) HSD11B1MEN1KMT2AMAPK1CHRM2
SCHEMBL785846 0.79 POLB (0.37) POLBKCNQ3KCNQ2KCNQ4KCNQ5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 327 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11370888-B2 Silicon-rich silsesquioxane resins DOW SILICONES CORPORATION (US) 2022-06-28 US claimed
US-20210380606-A1 5-AZAINDAZOLE DERIVATIVES AS ADENOSINE RECEPTOR ANTAGONISTS MERCK PATENT GMBH (DE) 2021-12-09 US claimed
US-20190211155-A1 SILICON-RICH SILSESQUIOXANE RESINS DOW SILICONES CORPORATION 2019-07-11 US claimed
US-8524439-B2 Silsesquioxane resin systems with base additives bearing electron-attracting functionalities DOW CORNING CORPORATION (US) 2013-09-03 US claimed
CN-101472955-B Olefin-acrylate-norbornene terpolymer and preparation method thereof LG CHEMICAL LTD 2013-02-20 CN claimed
CN-101987907-B Polydicyclopentadiene composite material and preparation method thereof UNIV HENAN SCIENCE & TECH 2012-07-04 CN claimed
US-8148043-B2 Silsesquioxane resin systems with base additives bearing electron-attracting functionalities DOW CORNING CORPORATION (US) 2012-04-03 US claimed
CN-101987907-A Polydicyclopentadiene composite material and preparation method thereof UNIV HENAN SCIENCE & TECH 2011-03-23 CN claimed
US-20090312467-A1 SILSESQUIOXANE RESIN SYSTEMS WITH BASE ADDITIVES BEARING ELECTRON-ATTRACTING FUNCTIONALITIES DOW CORNING CORPORATION (US) 2009-12-17 US claimed
US-20090202941-A1 SILSESQUIOXANE RESIN SYSTEMS WITH BASE ADDITIVES BEARING ELECTRON-ATTRACTING FUNCTIONALITIES DOW CORNING CORPORATION (US) 2009-08-13 US claimed
EP-1794161-A2 MUSCARINIC RECEPTOR ANTAGONISTS Ranbaxy Laboratories Limited (IN) 2007-06-13 EP claimed
WO-2007054813-A2 DEVELOPABLE UNDERCOATING COMPOSITION FOR THICK PHOTORESIST LAYERS AZ ELECTRONIC MATERIALS USA CORP. (DE) 2007-05-18 WO claimed
US-20070105040-A1 Developable undercoating composition for thick photoresist layers AZ ELECTRONIC MATERIALS USA CORP. 2007-05-10 US claimed
CN-1280321-C Photoetch resist copolymer HYNIX SEMICONDUCTOR INC (KR) 2006-10-18 CN claimed
WO-2006032994-A2 MUSCARINIC RECEPTOR ANTAGONISTS RANBAXY LABORATORIES LIMITED (IN) 2006-03-30 WO claimed
CN-1149237-C Copolymer resin, Preparation thereof, and photoresist using the same �ִ����Ӳ�ҵ��ʽ���� 2004-05-12 CN claimed
US-20030129531-A1 Positive-working photoimageable bottom antireflective coating MERCK PATENT GMBH (DE) 2003-07-10 US claimed
US-20020177066-A1 Silicon-containing copolymer and photosensitive resin composition containing the same INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE 2002-11-28 US claimed
CN-1226565-A Copolymer resin, preparation thereof, and photoresist using the same HYUNDAI ELECTRONICS IND (KR) 1999-08-25 CN claimed
CN-1187495-A Method and apparatus for using argon fluoride photoresist HYUNDAI ELECTRONICS IND (KR) 1998-07-15 CN claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210380606-A1 5-AZAINDAZOLE DERIVATIVES AS ADENOSINE RECEPTOR ANTAGONISTS ADORA2A, ADORA2B, ADORA1 POLB 1218/4885KCNQ3 3444/4885KCNQ2 3753/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.