Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.40 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.40 |
| ▸ | KCNQ4 | P56696 | 1/20 | 0.40 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7647668 | 1.00 | POLB (0.52) | POLBL3MBTL1HSD11B1HPGDKCNQ3 | |
| SCHEMBL2515949 | 0.86 | POLB (0.52) | POLBL3MBTL1HSD11B1HPGDKCNQ3 | |
| SCHEMBL7593658 | 0.84 | POLB (0.50) | POLBL3MBTL1HSD11B1HPGDKCNQ3 | |
| SCHEMBL1105066 | 0.83 | POLB (0.53) | POLBL3MBTL1HSD11B1KCNQ3KCNQ2 | |
| SCHEMBL28611784 | 0.83 | POLB (0.48) | POLBL3MBTL1HSD11B1HPGDKCNQ3 | |
| SCHEMBL34462074 | 0.83 | POLB (0.53) | POLBL3MBTL1HSD11B1KCNQ3KCNQ2 | |
| SCHEMBL18628997 | 0.83 | POLB (0.53) | POLBL3MBTL1HSD11B1KCNQ3KCNQ2 | |
| SCHEMBL17518655 | 0.83 | POLB (0.53) | POLBL3MBTL1HSD11B1KCNQ3KCNQ2 | |
| SCHEMBL32689262 | 0.81 | POLB (0.47) | POLBL3MBTL1HSD11B1HPGDKCNQ3 | |
| SCHEMBL21174561 | 0.79 | POLB (0.46) | POLBL3MBTL1HSD11B1HPGDKCNQ3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6491903-B1 | NARROW MOLECULAR WEIGHT DISTRIBUTION SHELL-CORE POLYMERS HAVING HYDROPHILIC, CROSSLINKED PERMEABLE SHELLS AND HYDROPHOBIC CORES, USED FOR REDUCING BLOOD CHOLESTEROL AND BILE ACID UPTAKE IN INTERSTINES; DRUG DELIVERY | WASHINGTON UNIVERSITY | 2002-12-10 | — | — | US | disclosed |
| US-6383500-B1 | Particles comprising amphiphilic copolymers, having a crosslinked shell domain and an interior core domain, useful for pharmaceutical and other applications | WASHINGTON UNIVERSITY | 2002-05-07 | — | — | US | disclosed |