SCHEMBL8772372

SCHEMBL8772372

O=C(c1ccc(-c2ccc(O)cc2)cc1)c1cccc(O)c1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.71
MAPT P10636 2/20 0.71
MEN1 O00255 2/20 0.71
RAB9A P51151 2/20 0.71
KMT2A Q03164 2/20 0.71
HSD17B1 P14061 8/20 0.69
HSD17B2 P37059 8/20 0.69
CLK1 P49759 1/20 0.68
DYRK1A Q13627 1/20 0.68
DYRK1B Q9Y463 1/20 0.68
FASN P49327 1/20 0.59
HTT P42858 2/20 0.58
ESR1 P03372 1/20 0.58
ESR2 Q92731 1/20 0.58
PKM P14618 1/20 0.58
HPGD P15428 1/20 0.58
NPC1 O15118 1/20 0.58
CA12 O43570 1/20 0.53
CA1 P00915 1/20 0.53
CA2 P00918 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27735439 0.94 CLK1 (0.75) LMNAMAPTMEN1RAB9AKMT2A
SCHEMBL189236 0.94 CLK1 (0.75) LMNAMAPTMEN1RAB9AKMT2A
SCHEMBL16561511 0.91 RAB9A (0.69) LMNAMAPTMEN1RAB9AKMT2A
SCHEMBL22717015 0.90 MEN1 (0.70) LMNAMAPTMEN1RAB9AKMT2A
SCHEMBL14148853 0.89 MEN1 (0.71) LMNAMAPTMEN1RAB9AKMT2A
SCHEMBL4678479 0.89 HSD17B1 (0.73) LMNAMAPTMEN1RAB9AKMT2A
SCHEMBL698836 0.86 LMNA (0.71) LMNAMAPTMEN1RAB9AKMT2A
SCHEMBL10395127 0.86 LMNA (0.71) LMNAMAPTMEN1RAB9AKMT2A
SCHEMBL29699163 0.85 FASN (0.76) LMNAMEN1RAB9AKMT2AHSD17B1
SCHEMBL809540 0.85 FASN (0.76) LMNAMEN1RAB9AKMT2AHSD17B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0289802-B1 Optically anisotropic melt forming aromatic copolyesters based on t-butyl-4-hydroxybenzoic acid DU PONT (US) 1997-10-15 EP claimed
EP-0242959-B1 OPTICALLY ANISOTROPIC MELT FORMING AROMATIC COPOLYESTERS BASED ON T-BUTYLHYDROQUINONE E.I. DU PONT DE NEMOURS AND COMPANY (US) 1990-10-03 EP claimed
EP-0289802-A2 Optically anisotropic melt forming aromatic copolyesters based on t-butyl-4-hydroxybenzoic acid E.I. DU PONT DE NEMOURS AND COMPANY (US) 1988-11-09 EP claimed
US-4746566-A Optically anisotropic melt forming aromatic copolyesters based on t-butyl-4-hydroxybenzoic acid E. I. DUPONT DE NEMOURS AND COMPANY (US) 1988-05-24 US claimed
EP-0242959-A2 Optically anisotropic melt forming aromatic copolyesters based on t-butylhydroquinone E.I. DU PONT DE NEMOURS AND COMPANY (US) 1987-10-28 EP claimed
US-4664972-A MOLDINGS, FIBERS, FILMS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1987-05-12 US claimed
EP-0289802-B1 Optically anisotropic melt forming aromatic copolyesters based on t-butyl-4-hydroxybenzoic acid DU PONT (US) 1997-10-15 EP disclosed
EP-0218366-B1 POLYESTER POLYMERS OF 3-HYDROXY-4'-(4-HYDROXYPHENYL) BENZOPHENONE OR 3,4'-DIHYDROXYBENZOPHENONE AND DICARBOXYLIC ACIDS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1990-11-22 EP disclosed
EP-0218366-B1 POLYESTER POLYMERS OF 3-HYDROXY-4'-(4-HYDROXYPHENYL) BENZOPHENONE OR 3,4'-DIHYDROXYBENZOPHENONE AND DICARBOXYLIC ACIDS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1990-11-22 EP disclosed
EP-0242959-B1 OPTICALLY ANISOTROPIC MELT FORMING AROMATIC COPOLYESTERS BASED ON T-BUTYLHYDROQUINONE E.I. DU PONT DE NEMOURS AND COMPANY (US) 1990-10-03 EP disclosed
EP-0289802-A2 Optically anisotropic melt forming aromatic copolyesters based on t-butyl-4-hydroxybenzoic acid E.I. DU PONT DE NEMOURS AND COMPANY (US) 1988-11-09 EP disclosed
EP-0169675-B1 OPTICALLY ANISTROPIC MELT FORMING COPOLYESTERS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1988-09-14 EP disclosed
US-4746566-A Optically anisotropic melt forming aromatic copolyesters based on t-butyl-4-hydroxybenzoic acid E. I. DUPONT DE NEMOURS AND COMPANY (US) 1988-05-24 US disclosed
US-4617369-A MELT ANISOTROPIC MOLDING MATERIALS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1986-10-14 US disclosed
US-4617369-A MELT ANISOTROPIC MOLDING MATERIALS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1986-10-14 US disclosed
EP-0169675-A1 Optically anistropic melt forming copolyesters E.I. DU PONT DE NEMOURS AND COMPANY (US) 1986-01-29 EP disclosed
US-4500699-A MONOSUBSTITUTED HYDROQUINONES, TEREPHTHALIC ACID, AND SUBSTITUTED BENZOPHENONES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1985-02-19 US disclosed
US-4245082-A Polyesters derived from 3,4'-dihydroxy-benzophenones or 3-hydroxy-4'-(4-hydroxyphenyl-)benzophenone and certain aromatic dicarboxylic acids and filaments thereof E. I. DU PONT DE NEMOURS AND COMPANY (US) 1981-01-13 US disclosed
US-4245082-A Polyesters derived from 3,4'-dihydroxy-benzophenones or 3-hydroxy-4'-(4-hydroxyphenyl-)benzophenone and certain aromatic dicarboxylic acids and filaments thereof E. I. DU PONT DE NEMOURS AND COMPANY (US) 1981-01-13 US disclosed
US-4245082-A Polyesters derived from 3,4'-dihydroxy-benzophenones or 3-hydroxy-4'-(4-hydroxyphenyl-)benzophenone and certain aromatic dicarboxylic acids and filaments thereof E. I. DU PONT DE NEMOURS AND COMPANY (US) 1981-01-13 US disclosed