SCHEMBL698836

SCHEMBL698836

O=C(c1ccc(O)cc1)c1cccc(C(=O)c2ccc(O)cc2)c1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.71
MAPT P10636 2/20 0.71
HTT P42858 2/20 0.71
ESR1 P03372 1/20 0.71
ESR2 Q92731 1/20 0.71
PKM P14618 1/20 0.71
HPGD P15428 1/20 0.71
TDP1 Q9NUW8 2/20 0.70
L3MBTL1 Q9Y468 2/20 0.70
ATM Q13315 1/20 0.70
MEN1 O00255 2/20 0.65
RAB9A P51151 2/20 0.65
KMT2A Q03164 2/20 0.65
NPC1 O15118 1/20 0.62
CLK1 P49759 1/20 0.62
DYRK1A Q13627 1/20 0.62
DYRK1B Q9Y463 1/20 0.62
SMN1; SMN2 Q16637 1/20 0.61
SRD5A2 P31213 1/20 0.60
STS P08842 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10395127 1.00 LMNA (0.71) LMNAMAPTHTTESR1ESR2
SCHEMBL29363432 0.92 SRD5A2 (0.69) LMNAMAPTHTTESR1ESR2
SCHEMBL10782270 0.92 SRD5A2 (0.76) LMNAMAPTHTTESR1ESR2
SCHEMBL3531 0.92 SRD5A2 (0.69) LMNAMAPTHTTESR1ESR2
SCHEMBL27735439 0.91 CLK1 (0.75) LMNAMAPTHTTESR1ESR2
SCHEMBL189236 0.91 CLK1 (0.75) LMNAMAPTHTTESR1ESR2
SCHEMBL10783506 0.90 LMNA (0.61) LMNAMAPTHTTESR1ESR2
SCHEMBL5079227 0.88 MEN1 (0.76) LMNAMAPTHTTESR1ESR2
SCHEMBL31574444 0.87 HTT (0.83) LMNAMAPTHTTESR1ESR2
SCHEMBL22717015 0.87 MEN1 (0.70) LMNAMAPTHTTESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 264 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240360279-A1 HIGH-STRENGTH AND LOW-CHROMA POLYETHERETHERKETONE AND PREPARATION METHOD THEREFOR JILIN JOINATURE POLYMER CO., LTD. (CN) 2024-10-31 US claimed
CN-113651954-B Composition for synthesizing polyether-ether-ketone, synthetic method of polyether-ether-ketone and polyether-ether-ketone 吉林省中研高分子材料股份有限公司 2024-07-19 CN claimed
EP-4372028-A1 HIGH-STRENGTH AND LOW-CHROMA POLYETHER ETHER KETONE AND PREPARATION METHOD THEREFOR Jilin Joinature Polymer Co., Ltd. (CN) 2024-05-22 EP claimed
CN-113563578-B Method for preparing poly (aryl ether ketone) and poly (aryl ether ketone) 吉林省中研高分子材料股份有限公司 2023-12-26 CN claimed
CN-113583233-B Method for preparing poly (aryl ether ketone) by premixing and poly (aryl ether ketone) 吉林省中研高分子材料股份有限公司 2023-08-04 CN claimed
CN-113527661-B Preparation method of poly (aryl ether ketone) and poly (aryl ether ketone) 吉林省中研高分子材料股份有限公司 2022-07-15 CN claimed
CN-112961340-B Quaternary copolymerized polyaryletherketone, and preparation method and application thereof 吉林大学 2022-06-10 CN claimed
CN-113583232-B High-strength low-chroma polyether-ether-ketone and preparation method thereof 吉林省中研高分子材料股份有限公司 2022-03-22 CN claimed
CN-113651954-A Composition for synthesizing polyether-ether-ketone, synthesis method of polyether-ether-ketone and polyether-ether-ketone 吉林省中研高分子材料股份有限公司 2021-11-16 CN claimed
CN-113583233-A Method for preparing poly (aryl ether ketone) by premixing and poly (aryl ether ketone) 吉林省中研高分子材料股份有限公司 2021-11-02 CN claimed
EP-3443020-A1 POLYISOINDOLINONES, METHODS OF MANUFACTURE, AND COMPOSITIONS AND ARTICLES FORMED THEREFROM SABIC Global Technologies B.V. (NL) 2019-02-20 EP claimed
EP-3443021-A1 POLYISOINDOLINONE COMPOSITIONS, METHODS OF MANUFACTURE, AND COMPOSITIONS AND ARTICLES FORMED THEREFROM SABIC Global Technologies B.V. (NL) 2019-02-20 EP claimed
US-9815937-B2 Process for preparing a poly(aryl ether ketone) using a high purity 4,4′-difluorobenzophenone SOLVAY ADVANCED POLYMERS, L.L.C. (US) 2017-11-14 US claimed
WO-2017180972-A1 POLYISOINDOLINONE COMPOSITIONS, METHODS OF MANUFACTURE, AND COMPOSITIONS AND ARTICLES FORMED THEREFROM SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2017-10-19 WO claimed
WO-2017180556-A1 POLYISOINDOLINONES, METHODS OF MANUFACTURE, AND COMPOSITIONS AND ARTICLES FORMED THEREFROM SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2017-10-19 WO claimed
EP-2588513-B1 METHOD OF MAKING POLY(ARYL ETHER KETONES) FROM 4,4' DIFLUOROBENZOPHENONE COMPRISING OXIDIZING SPECIES AND/OR NITRO COMPOUNDS SOLVAY SPECIALTY POLYMERS USA (US) 2017-10-04 EP claimed
US-20160145386-A1 PROCESS FOR PREPARING A POLY(ARYL ETHER KETONE) USING A HIGH PURITY 4,4'- DIFLUOROBENZOPHENONE SOLVAY ADVANCED POLYMERS, L.L.C. (US) 2016-05-26 US claimed
EP-2342259-B1 IMPROVED PROCESS FOR PREPARING A POLY(ARYL ETHER KETONE) USING A HIGH PURITY 4,4'-DIFLUOROBENZOPHENONE SOLVAY SPECIALTY POLYMERS USA (US) 2013-08-07 EP claimed
US-20110213115-A1 Process for preparing a poly(aryl ether ketone) using a high purity 4,4'-difluorobenzophenone SOLVAY ADVANCED POLYMERS, L.L.C. (US) 2011-09-01 US claimed
US-4939199-A Novel poly(aryl ethers) useful for molding into a circuit board substrate AMOCO CORPORATION (US) 1990-07-03 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160145386-A1 PROCESS FOR PREPARING A POLY(ARYL ETHER KETONE) USING A HIGH PURITY 4,4'- DIFLUOROBENZOPHENONE HNF4A, CUL4B, CUL4A LMNA 4016/4885MAPT 4600/4885HTT 3637/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.