Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17570945 | 1.00 | FAAH (0.43) | FAAHTSHRCASP1SMN1; SMN2SLC6A5 | |
| SCHEMBL6444837 | 0.90 | EPHX2 (0.44) | TSHRSMN1; SMN2EPHX2ALDH1A1RECQL | |
| SCHEMBL17570970 | 0.86 | FAAH (0.50) | FAAHTSHRSMN1; SMN2SLC6A5ALDH1A1 | |
| SCHEMBL17570951 | 0.86 | FAAH (0.50) | FAAHTSHRSMN1; SMN2SLC6A5ALDH1A1 | |
| SCHEMBL622468 | 0.86 | EPHX2 (0.48) | FAAHTSHRSMN1; SMN2EPHX2ALDH1A1 | |
| SCHEMBL6446232 | 0.86 | EPHX2 (0.48) | FAAHTSHRSMN1; SMN2EPHX2ALDH1A1 | |
| SCHEMBL23071837 | 0.85 | FAAH (0.46) | FAAHCASP1SMN1; SMN2SLC6A5EPHX2 | |
| SCHEMBL30076306 | 0.85 | FAAH (0.60) | FAAHSMN1; SMN2SLC6A5ALDH1A1 | |
| SCHEMBL6445084 | 0.84 | EPHX2 (0.50) | FAAHTSHRSMN1; SMN2EPHX2ALDH1A1 | |
| SCHEMBL6445088 | 0.84 | EPHX2 (0.50) | FAAHTSHRSMN1; SMN2EPHX2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9669102-B2 | Cytotoxic benzodiazepine derivatives | IMMUNOGEN, INC. (US) | 2017-06-06 | — | — | US | disclosed |