Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.35 |
| ▸ | NOS3 | P29474 | 1/20 | 0.35 |
| ▸ | NOS1 | P29475 | 1/20 | 0.35 |
| ▸ | NOS2 | P35228 | 1/20 | 0.35 |
| ▸ | ADH1B | P00325 | 1/20 | 0.34 |
| ▸ | ADH1C | P00326 | 1/20 | 0.34 |
| ▸ | ADH1A | P07327 | 1/20 | 0.34 |
| ▸ | ADH4 | P08319 | 1/20 | 0.34 |
| ▸ | ADH7 | P40394 | 1/20 | 0.34 |
| ▸ | GSR | P00390 | 2/20 | 0.34 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.33 |
| ▸ | METAP1 | P53582 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL497088 | 1.00 | TSHR (0.36) | TSHREPHX1NOS3NOS1NOS2 | |
| SCHEMBL18202924 | 1.00 | TSHR (0.36) | TSHREPHX1NOS3NOS1NOS2 | |
| SCHEMBL9452653 | 0.97 | — | — | |
| SCHEMBL28982087 | 0.92 | — | — | |
| SCHEMBL1483957 | 0.86 | — | — | |
| Ethyl Acetate SCHEMBL3819307 | 0.78 | ALDH1A1 (0.45) | POLBKMT2A | |
| SCHEMBL9151261 | 0.75 | TSHR (0.33) | TSHR | |
| SCHEMBL261756 | 0.75 | TSHR (0.33) | TSHR | |
| SCHEMBL3962160 | 0.75 | NOS3 (0.49) | TSHREPHX1NOS3NOS1NOS2 | |
| SCHEMBL3020091 | 0.75 | TSHR (0.33) | TSHRNOS3NOS1NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9668646-B2 | Devices and methods for a contact lens with an inward facing light source | VERILY LIFE SCIENCES LLC (US) | 2017-06-06 | — | — | US | disclosed |