Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.35 |
| ▸ | NOS3 | P29474 | 1/20 | 0.35 |
| ▸ | NOS1 | P29475 | 1/20 | 0.35 |
| ▸ | NOS2 | P35228 | 1/20 | 0.35 |
| ▸ | ADH1B | P00325 | 1/20 | 0.34 |
| ▸ | ADH1C | P00326 | 1/20 | 0.34 |
| ▸ | ADH1A | P07327 | 1/20 | 0.34 |
| ▸ | ADH4 | P08319 | 1/20 | 0.34 |
| ▸ | ADH7 | P40394 | 1/20 | 0.34 |
| ▸ | GSR | P00390 | 2/20 | 0.34 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.33 |
| ▸ | METAP1 | P53582 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18202924 | 1.00 | TSHR (0.36) | TSHREPHX1NOS3NOS1NOS2 | |
| SCHEMBL18924168 | 1.00 | TSHR (0.36) | TSHREPHX1NOS3NOS1NOS2 | |
| SCHEMBL9452653 | 0.97 | — | — | |
| SCHEMBL28982087 | 0.92 | — | — | |
| SCHEMBL1483957 | 0.86 | — | — | |
| Ethyl Acetate SCHEMBL3819307 | 0.78 | ALDH1A1 (0.45) | POLBKMT2A | |
| SCHEMBL9151261 | 0.75 | TSHR (0.33) | TSHR | |
| SCHEMBL261756 | 0.75 | TSHR (0.33) | TSHR | |
| SCHEMBL3962160 | 0.75 | NOS3 (0.49) | TSHREPHX1NOS3NOS1NOS2 | |
| SCHEMBL3020091 | 0.75 | TSHR (0.33) | TSHRNOS3NOS1NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 154 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0414274-B1 | PROCESS FOR THE PREPARATION OF 1 AMINOMETHYL-1.CYCLOHEXANACETIC ACID | GÖDECKE AKTIENGESELLSCHAFT (DE) | 1993-06-23 | — | — | EP | claimed |
| US-12032290-B2 | Actinic ray-sensitive or radiation-sensitive resin composition, resist film, pattern forming method, and method for manufacturing electronic device | FUJIFILM CORPORATION (JP) | 2024-07-09 | — | — | US | disclosed |
| CN-106631809-B | Green synthesis method for preparing nitroalkane by oxidizing oxime | 南京工业大学 | 2019-02-22 | — | — | CN | disclosed |
| CN-106631809-A | Green synthesis method for preparing nitroalkane by oxidizing oxime | 南京工业大学 | 2017-05-10 | — | — | CN | disclosed |
| US-9428507-B2 | Compounds for the treatment of malaria | THE BROAD INSTITUTE, INC. (US) | 2016-08-30 | — | — | US | disclosed |
| US-9067911-B2 | Piperidine derivatives | HOFFMANN-LA ROCHE INC. (US) | 2015-06-30 | — | — | US | disclosed |
| US-8796399-B2 | Polyethersulfone compositions with high heat and good impact resistance | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2014-08-05 | — | — | US | disclosed |
| EP-1555266-B1 | REMEDIES OR PREVENTIVES FOR URINARY INCONTINENCE AND MORPHINAN DERIVATIVES HAVING NITROGEN-CONTAINING HETEROCYCLIC GROUP | TORAY INDUSTRIES (JP) | 2014-05-21 | — | — | EP | disclosed |
| EP-2391603-B1 | AROYLAMINO - AND HETEROAROYLAMINO-SUBSTITUTED PIPERIDINES AS GLYT-1 INHIBITORS | HOFFMANN LA ROCHE (CH) | 2014-01-08 | — | — | EP | disclosed |
| US-8623971-B2 | Polyethersulfone compositions with high heat and good impact resistance | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2014-01-07 | — | — | US | disclosed |
| EP-1140793-A1 | PROCESS FOR THE SYNTHESIS OF 1-(AMINOMETHYL)CYCLOHEXYL-ACETIC ACID | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000039074-A1 | PROCESS FOR THE SYNTHESIS OF 1-(AMINOMETHYL)CYCLOHEXYL-ACETIC ACID | Richter Gedeon Vegyészeti Gyár Rt. (HU) | 2000-07-06 | — | — | WO | disclosed |
| EP-0341496-B1 | Modified diene polymer rubbers | SUMITOMO CHEMICAL CO (JP) | 1993-10-20 | — | — | EP | disclosed |
| US-5219938-A | Reacting a living polymer of a conjugated diene with a tin or silicon compound and with a nitro compound, a phosphoryl chloride, aminosilane, an acrylamide or an aminovinylsilane; auto tires; impact strength; cold resistance; storage | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1993-06-15 | — | — | US | disclosed |
| US-5128416-A | Automobile tire treads | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1992-07-07 | — | — | US | disclosed |
| US-5015692-A | Rubbers for tires having impact strength | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1991-05-14 | — | — | US | disclosed |
| US-4957976-A | IMPROVED PROPERTIES FOR AUTOMOBILE TIRES, MODIFIED WITH PHOSPHORYL CHLORIDE | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1990-09-18 | — | — | US | disclosed |
| EP-0341496-A2 | Modified diene polymer rubbers | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1989-11-15 | — | — | EP | disclosed |
| EP-0270071-A2 | Process for preparing modified diene polymer rubbers | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1988-06-08 | — | — | EP | disclosed |
| US-3954823-A | Interconversion of stereoisomeric cycloorganosiloxanes | DOW CORNING CORPORATION (US) | 1976-05-04 | — | — | US | disclosed |