SCHEMBL18924199

SCHEMBL18924199

Cc1cc2oc3cc(=O)c(C)cc-3nc2cc1S(C)(=O)=O

nearest known ligand 0.38

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.38
KDM4E B2RXH2 1/20 0.38
MEN1 O00255 1/20 0.38
ALDH1A1 P00352 1/20 0.38
ALPL P05186 1/20 0.38
POLB P06746 1/20 0.38
ALPI P09923 1/20 0.38
MAPT P10636 1/20 0.38
ALPG P10696 1/20 0.38
RECQL P46063 1/20 0.38
RAB9A P51151 1/20 0.38
KMT2A Q03164 1/20 0.38
SNCA P37840 1/20 0.37
APP P05067 4/20 0.33
CYP1A2 P05177 1/20 0.32
ADORA3 P0DMS8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12952317 0.73 SNCA (0.44) L3MBTL1KDM4EMEN1ALDH1A1ALPL
SCHEMBL2609271 0.73 MAPT (0.68) L3MBTL1KDM4EMEN1ALDH1A1ALPL
SCHEMBL327849 0.72 APP (0.63) L3MBTL1KDM4EMEN1ALDH1A1ALPL
SCHEMBL16069586 0.69 KMT2A (0.32) KMT2A
SCHEMBL18924217 0.69 KDM4E (0.43) L3MBTL1KDM4EMEN1ALDH1A1ALPL
SCHEMBL1748015 0.63 SMN1; SMN2 (0.37) KDM4EALDH1A1MAPTRAB9AKMT2A
SCHEMBL10145471 0.62 KDM4E (0.38) L3MBTL1KDM4EMEN1ALDH1A1ALPL
SCHEMBL10145461 0.62 LMNA (0.39) L3MBTL1KDM4EMEN1ALDH1A1ALPL
SCHEMBL8776059 0.61 CSNK2A2 (0.34) L3MBTL1KDM4EMEN1ALDH1A1ALPL
SCHEMBL13676278 0.60 MEN1 (0.39) L3MBTL1KDM4EMEN1ALDH1A1ALPL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9670170-B2 Resorufin derivatives for treatment of oxidative stress disorders BIOELECTRON TECHNOLOGY CORPORATION (US) 2017-06-06 US disclosed