Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10289399 | 0.81 | PIK3CD (0.48) | PIK3CDRAB9AKCNA5 | |
| SCHEMBL19364040 | 0.81 | PIK3CD (0.38) | PIK3CDRAB9A | |
| SCHEMBL4733460 | 0.75 | PIK3CD (0.43) | PIK3CDRAB9AKCNA5 | |
| SCHEMBL13407603 | 0.75 | FDPS (0.33) | KCNA5 | |
| SCHEMBL24577584 | 0.74 | PIK3CD (0.39) | PIK3CDRAB9AKCNA5 | |
| SCHEMBL22844795 | 0.73 | MEN1 (0.38) | — | |
| SCHEMBL12703399 | 0.73 | KCNA5 (0.43) | PIK3CDRAB9AKCNA5 | |
| SCHEMBL19083710 | 0.73 | PIK3CD (0.41) | PIK3CDRAB9AKCNA5 | |
| SCHEMBL19909618 | 0.73 | PIK3CD (0.58) | PIK3CDRAB9AKCNA5 | |
| SCHEMBL15696992 | 0.72 | PIK3CD (0.34) | PIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9670196-B2 | Thiazole-substituted aminoheteroaryls as Spleen Tyrosine Kinase inhibitors | MERCK SHARP & DOHME CORP. (US) | 2017-06-06 | — | — | US | disclosed |