Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19364067 | 0.79 | MEN1 (0.37) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL24875931 | 0.79 | MEN1 (0.40) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL79660 | 0.79 | MAPT (0.42) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL13407603 | 0.78 | FDPS (0.33) | — | |
| Water SCHEMBL3302021 | 0.76 | MAPT (0.40) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL12790540 | 0.76 | MAPT (0.40) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL10170630 | 0.74 | ALDH1A1 (0.35) | ALDH1A1 | |
| SCHEMBL10170330 | 0.74 | PHF8 (0.35) | ALDH1A1KDM4E | |
| SCHEMBL18924283 | 0.73 | PIK3CD (0.39) | — | |
| SCHEMBL1404128 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12043833-B2 | Targeted compositions | ARBUTUS BIOPHARMA CORPORATION (CA) | 2024-07-23 | — | — | US | disclosed |
| US-20200407724-A1 | TARGETED COMPOSITIONS | ARBUTUS BIOPHARMA CORPORATION (CA) | 2020-12-31 | — | — | US | disclosed |