Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.45 |
| ▸ | FASN | P49327 | 1/20 | 0.44 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.44 |
| ▸ | DRD1 | P21728 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18924563 | 0.83 | MCHR1 (0.59) | MEN1KMT2ALMNAMAPTALDH1A1 | |
| SCHEMBL18924525 | 0.80 | KCNH2 (0.57) | MEN1KMT2AALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL18924383 | 0.79 | ALDH1A1 (0.53) | MEN1KMT2ALMNAMAPTALDH1A1 | |
| SCHEMBL16324241 | 0.78 | FASN (0.75) | FASN | |
| SCHEMBL16365083 | 0.78 | FASN (0.75) | FASN | |
| SCHEMBL18924387 | 0.78 | MCHR1 (0.56) | MEN1KMT2ALMNAMAPTPOLB | |
| SCHEMBL18924526 | 0.78 | MCHR1 (0.62) | MCHR1 | |
| SCHEMBL9001766 | 0.78 | ALDH1A1 (0.66) | MEN1KMT2ALMNAMAPTALDH1A1 | |
| SCHEMBL9001761 | 0.77 | USP30 (0.59) | MEN1KMT2ALMNAMAPTALDH1A1 | |
| SCHEMBL11406234 | 0.77 | KMT2A (0.64) | MEN1KMT2ALMNAMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9670142-B2 | 1,3-diaminocyclopentane carboxamide derivatives | MERCK PATENT GMBH (DE) | 2017-06-06 | — | — | US | disclosed |