Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 10/20 | 0.56 |
| ▸ | PARP15 | Q460N3 | 4/20 | 0.53 |
| ▸ | PARP10 | Q53GL7 | 4/20 | 0.53 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16365761 | 0.84 | MCHR1 (0.52) | MCHR1PARP15PARP10PARP2 | |
| SCHEMBL18924563 | 0.82 | MCHR1 (0.59) | MCHR1MEN1KMT2ALMNAMAPT | |
| SCHEMBL16324054 | 0.79 | FASN (0.72) | MCHR1 | |
| SCHEMBL19391364 | 0.79 | FASN (0.72) | MCHR1 | |
| SCHEMBL7733823 | 0.78 | PARP15 (0.66) | PARP15PARP10PARP2MEN1KMT2A | |
| SCHEMBL7737448 | 0.78 | PARP10 (0.66) | PARP15PARP10PARP2MEN1KMT2A | |
| SCHEMBL18924339 | 0.78 | MEN1 (0.53) | MCHR1MEN1KMT2ALMNAMAPT | |
| SCHEMBL18924383 | 0.78 | ALDH1A1 (0.53) | MEN1KMT2ALMNAMAPTPOLB | |
| SCHEMBL9001766 | 0.77 | ALDH1A1 (0.66) | MEN1KMT2ALMNAMAPTPOLB | |
| SCHEMBL9001761 | 0.76 | USP30 (0.59) | MEN1KMT2ALMNAMAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9670142-B2 | 1,3-diaminocyclopentane carboxamide derivatives | MERCK PATENT GMBH (DE) | 2017-06-06 | — | — | US | disclosed |