Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | DPP4 | P27487 | 1/20 | 0.49 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.49 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.49 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.49 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.49 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.49 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | FASN | P49327 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11406234 | 0.94 | KMT2A (0.64) | MCHR1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL10454995 | 0.94 | KMT2A (0.64) | MCHR1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL18924561 | 0.85 | MCHR1 (0.64) | MCHR1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL13605546 | 0.84 | CSNK2A1 (0.55) | MCHR1MEN1KMT2ATRPM8ALDH1A1 | |
| SCHEMBL18924431 | 0.84 | MAPK14 (0.53) | MCHR1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL18924339 | 0.83 | MEN1 (0.53) | MCHR1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL18924383 | 0.83 | ALDH1A1 (0.53) | MEN1KMT2ANPC1RAB9ALMNA | |
| SCHEMBL18924387 | 0.82 | MCHR1 (0.56) | MCHR1MEN1KMT2ALMNAMAPT | |
| SCHEMBL24494256 | 0.82 | DPP4 (0.52) | MCHR1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL28628582 | 0.82 | MCHR1 (0.50) | MCHR1MEN1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3010916-B1 | 1,3-DIAMINOCYCLOPENTANE CARBOXAMIDE DERIVATIVES | MERCK PATENT GMBH (DE) | 2017-09-27 | — | — | EP | disclosed |
| US-9670142-B2 | 1,3-diaminocyclopentane carboxamide derivatives | MERCK PATENT GMBH (DE) | 2017-06-06 | — | — | US | disclosed |