Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.33 |
| ▸ | CSF1R | P07333 | 2/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 2/20 | 0.32 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.32 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.32 |
| ▸ | PTGES | O14684 | 1/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.31 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.31 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19821854 | 0.82 | ABL1 (0.38) | IDO1NOTUMCSF1RMEN1KMT2A | |
| SCHEMBL10472195 | 0.79 | MAPT (0.36) | IDO1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL10472196 | 0.79 | MAPT (0.36) | IDO1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL21503622 | 0.77 | SMN1; SMN2 (0.43) | IDO1NOTUMCSF1RMEN1KMT2A | |
| SCHEMBL12151773 | 0.77 | PDE10A (0.43) | IDO1NOTUMCSF1RMEN1KMT2A | |
| SCHEMBL24973095 | 0.76 | KMT2A (0.41) | MEN1KMT2AGABRA1SMN1; SMN2 | |
| SCHEMBL11502287 | 0.74 | RAB9A (0.50) | IDO1MEN1KMT2AL3MBTL1NPC1 | |
| SCHEMBL18924321 | 0.74 | CPB2 (0.50) | GABRA1 | |
| SCHEMBL19822092 | 0.74 | ALDH1A1 (0.41) | L3MBTL1SMN1; SMN2 | |
| SCHEMBL24974211 | 0.74 | CYP11B1 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9670172-B2 | Heterocyclic compounds and methods of use | MEDIVATION TECHNOLOGIES, INC. (US) | 2017-06-06 | — | — | US | disclosed |