Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NSD2 | O96028 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | MMP3 | P08254 | 2/20 | 0.48 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.48 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.48 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.48 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.48 |
| ▸ | ERN1 | O75460 | 2/20 | 0.47 |
| ▸ | GSK3B | P49841 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 3/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | MMP8 | P22894 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10933810 | 0.94 | NSD2 (0.55) | NSD2CA1CA2ALDH1A1HPGD | |
| SCHEMBL22259646 | 0.89 | NSD2 (0.51) | NSD2CA1CA2ALDH1A1HPGD | |
| SCHEMBL10626283 | 0.84 | ALDH1A1 (0.64) | ALDH1A1HPGDSMN1; SMN2PDK2ERN1 | |
| SCHEMBL30020530 | 0.81 | ERN1 (0.43) | NSD2ALDH1A1HPGDSMN1; SMN2PDK1 | |
| SCHEMBL24690186 | 0.81 | ERN1 (0.43) | NSD2ALDH1A1HPGDSMN1; SMN2PDK1 | |
| SCHEMBL13151106 | 0.81 | NSD2 (0.54) | NSD2CA1CA2ALDH1A1HPGD | |
| SCHEMBL10058042 | 0.79 | MAPT (0.66) | CA1CA2ALDH1A1SMN1; SMN2MMP3 | |
| SCHEMBL5318807 | 0.77 | ALDH1A1 (0.52) | ALDH1A1HPGDSMN1; SMN2PDK2ERN1 | |
| SCHEMBL1004649 | 0.77 | ALDH1A1 (0.73) | ALDH1A1HPGDSMN1; SMN2PDK2ERN1 | |
| SCHEMBL20812229 | 0.76 | TRPA1 (0.56) | NSD2CA1CA2ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020150423-A1 | METHODS FOR THE TREATMENT OF NEUROLOGICAL DISORDERS | YUMANITY THERAPEUTICS, INC. (US) | 2020-07-23 | — | — | WO | disclosed |
| US-9670142-B2 | 1,3-diaminocyclopentane carboxamide derivatives | MERCK PATENT GMBH (DE) | 2017-06-06 | — | — | US | disclosed |