Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.73 |
| ▸ | HPGD | P15428 | 4/20 | 0.73 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.73 |
| ▸ | ERN1 | O75460 | 2/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.46 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | MMP8 | P22894 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10626283 | 0.92 | ALDH1A1 (0.64) | ALDH1A1HPGDSMN1; SMN2ERN1PDK2 | |
| SCHEMBL469413 | 0.89 | ALDH1A1 (0.61) | ALDH1A1HPGDSMN1; SMN2ERN1MEN1 | |
| SCHEMBL487487 | 0.89 | HPGD (0.61) | ALDH1A1HPGDSMN1; SMN2ERN1HSP90AA1 | |
| SCHEMBL949041 | 0.89 | HPGD (0.61) | ALDH1A1HPGDSMN1; SMN2ERN1HSP90AA1 | |
| SCHEMBL1300109 | 0.89 | ALDH1A1 (0.61) | ALDH1A1HPGDSMN1; SMN2ERN1HSP90AA1 | |
| SCHEMBL458926 | 0.89 | ALDH1A1 (0.61) | ALDH1A1HPGDSMN1; SMN2MEN1TP53 | |
| SCHEMBL24783913 | 0.87 | ALDH1A1 (0.67) | ALDH1A1HPGDSMN1; SMN2HSP90AA1PDK2 | |
| SCHEMBL9923439 | 0.87 | ALDH1A1 (0.59) | ALDH1A1HPGDSMN1; SMN2ERN1HSP90AA1 | |
| SCHEMBL642860 | 0.87 | ALDH1A1 (0.59) | ALDH1A1HPGDSMN1; SMN2ERN1MAPT | |
| SCHEMBL2212261 | 0.87 | ALDH1A1 (0.59) | ALDH1A1HPGDSMN1; SMN2ERN1HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9878975-B2 | Catalytic hydrogenation for producing amines from carboxylic acid amides, carboxylic acid diamides, di-, tri-, or polypeptides, or peptide amides | EVONIK DEGUSSA GMBH (DE) | 2018-01-30 | — | — | US | claimed |
| US-5338644-A | Form complexes with N,N,N*,N*-tetrasubstituted diamides of aromatic dicarboxylic acids to prevent migration of hydroquinones puring storage | POLAROID CORPORATION (US) | 1994-08-16 | — | — | US | claimed |
| US-5177262-A | Hydrogen-Bonded Complex with N,N,N',N'-Tetrasubstituted P-Aromatic Dicarboxamides | POLAROID CORPORATION (US) | 1993-01-05 | — | — | US | claimed |
| CN-111225940-B | Polymerization process | 杜邦聚合物公司 | 2023-10-10 | — | — | CN | disclosed |
| US-9878975-B2 | Catalytic hydrogenation for producing amines from carboxylic acid amides, carboxylic acid diamides, di-, tri-, or polypeptides, or peptide amides | EVONIK DEGUSSA GMBH (DE) | 2018-01-30 | — | — | US | disclosed |
| US-20160272571-A1 | Catalytic Hydrogenation for Producing Amines from Carboxylic Acid Amides, Carboxylic Acid Diamides, Di-, Tri-, or Polypeptides, or Peptide Amides | EVONIK DEGUSSA GMBH (DE) | 2016-09-22 | — | — | US | disclosed |
| EP-3066065-A1 | CATALYTIC HYDROGENATION FOR PRODUCING AMINES FROM CARBOXYLIC ACID AMIDES, CARBOXYLIC ACID DIAMIDES, DI-, TRI-, OR POLYPEPETIDES, OR PEPTIDE AMIDES | Evonik Degussa GmbH (DE) | 2016-09-14 | — | — | EP | disclosed |
| WO-2015067450-A1 | CATALYTIC HYDROGENATION FOR PRODUCING AMINES FROM CARBOXYLIC ACID AMIDES, CARBOXYLIC ACID DIAMIDES, DI-, TRI-, OR POLYPEPETIDES, OR PEPTIDE AMIDES | EVONIK INDUSTRIES AG (DE) | 2015-05-14 | — | — | WO | disclosed |
| EP-2868643-A1 | Catalytic hydrogenation for the preparation of amines from carboxylic acid amides, carboxylic acid amides, di-, tri- or polypeptides or peptide amides | Evonik Industries AG (DE) | 2015-05-06 | — | — | EP | disclosed |
| US-8778219-B2 | Ionic liquids for separation of olefin-paraffin mixtures | UT-BATTELLE, LLC (US) | 2014-07-15 | — | — | US | disclosed |
| US-20140107135-A1 | PYRIMIDINONE INHIBITORS OF LIPOPROTEIN-ASSOCIATED PHOSPHOLIPASE A2 | AUSPEX PHARMACEUTICALS, INC. (US) | 2014-04-17 | — | — | US | disclosed |
| EP-0523470-B1 | Complexed hydroquinones | POLAROID CORP (US) | 1997-03-19 | — | — | EP | disclosed |
| EP-0496264-B1 | Process for preparing 2,6-naphthalenedicarboxylic acid | MITSUBISHI CHEM CORP (JP) | 1995-11-29 | — | — | EP | disclosed |
| US-5338644-A | Form complexes with N,N,N*,N*-tetrasubstituted diamides of aromatic dicarboxylic acids to prevent migration of hydroquinones puring storage | POLAROID CORPORATION (US) | 1994-08-16 | — | — | US | disclosed |
| EP-0523470-A2 | Complexed hydroquinones | POLAROID CORPORATION (US) | 1993-01-20 | — | — | EP | disclosed |
| US-5177262-A | Hydrogen-Bonded Complex with N,N,N',N'-Tetrasubstituted P-Aromatic Dicarboxamides | POLAROID CORPORATION (US) | 1993-01-05 | — | — | US | disclosed |
| US-5175352-A | PROCESS FOR PREPARING 2,6-NAPHTHALENEDICARBOXYLIC ACID | MITSUBISHI PETROCHEMICAL CO., LTD. (JP) | 1992-12-29 | — | — | US | disclosed |
| EP-0518861-A1 | PROCESS FOR OBTAINING PHOSPHOROUS ACID-BIS-(2,4-DI-TERT.-BUTYL-PHENYL) ESTER HALIDES. | HOECHST AG (DE) | 1992-12-23 | — | — | EP | disclosed |
| EP-0496264-A2 | Process for preparing 2,6-naphthalenedicarboxylic acid | Mitsubishi Chemical Corporation (JP) | 1992-07-29 | — | — | EP | disclosed |
| WO-1991007415-A1 | PROCESS FOR OBTAINING PHOSPHOROUS ACID-BIS-(2,4-DI-TERT.-BUTYL-PHENYL) ESTER HALIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-05-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140107135-A1 | PYRIMIDINONE INHIBITORS OF LIPOPROTEIN-ASSOCIATED PHOSPHOLIPASE A2 | PLA2G1B, PLA2G4A, PLA2G4B | ALDH1A1 1423/4885HPGD 610/4885SMN1; SMN2 4141/4885 |
| US-20160272571-A1 | Catalytic Hydrogenation for Producing Amines from Carboxylic Acid Amides, Carboxylic Acid Diamides, Di-, Tri-, or Polypeptides, or Peptide Amides | DAO, DDC, HDGF | ALDH1A1 2121/4885HPGD 1640/4885SMN1; SMN2 4055/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.