Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 11/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.42 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | FASN | P49327 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19391089 | 0.85 | MAPK14 (0.46) | SLC6A4SLC6A2USP30POLBNPC1 | |
| SCHEMBL18924392 | 0.84 | MAPK14 (0.44) | POLBNPC1RAB9AALDH1A1GAA | |
| SCHEMBL22221034 | 0.84 | LMNA (0.43) | SLC6A4SLC6A2ALDH1A1SMN1; SMN2 | |
| SCHEMBL16323476 | 0.82 | FASN (0.66) | FASN | |
| SCHEMBL18924424 | 0.76 | MAPK14 (0.41) | USP30POLBNPC1RAB9AFASN | |
| SCHEMBL18924576 | 0.75 | EGLN1 (0.41) | SLC6A4SLC6A2USP30POLBFASN | |
| SCHEMBL18924454 | 0.75 | DYRK1A (0.49) | POLBNPC1RAB9AALDH1A1GAA | |
| SCHEMBL18924529 | 0.74 | POLB (0.46) | POLBNPC1RAB9AALDH1A1GAA | |
| SCHEMBL19391338 | 0.74 | FASN (0.64) | USP30POLBNPC1RAB9AFASN | |
| SCHEMBL16365762 | 0.73 | POLB (0.52) | POLBNPC1RAB9AALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9670142-B2 | 1,3-diaminocyclopentane carboxamide derivatives | MERCK PATENT GMBH (DE) | 2017-06-06 | — | — | US | disclosed |