Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 8/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | FASN | P49327 | 2/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19391089 | 0.86 | MAPK14 (0.46) | EGLN1POLBFASNUSP30SLC6A4 | |
| SCHEMBL16323967 | 0.84 | FASN (0.59) | EGLN1FASN | |
| SCHEMBL22259622 | 0.83 | FASN (0.46) | EGLN1FASNHTR2CKCNH2MCHR1 | |
| SCHEMBL19391173 | 0.80 | FASN (0.48) | EGLN1POLBFASNHTR2CKCNH2 | |
| SCHEMBL18924422 | 0.77 | MCHR1 (0.45) | EGLN1POLBFASNHTR2CKCNH2 | |
| SCHEMBL18924390 | 0.75 | SLC6A4 (0.47) | EGLN1POLBFASNUSP30SLC6A4 | |
| SCHEMBL19391174 | 0.72 | POLB (0.44) | EGLN1POLBFASNHTR2CKCNH2 | |
| SCHEMBL22259806 | 0.72 | PRKAB2 (0.46) | — | |
| SCHEMBL16323465 | 0.71 | FASN (0.66) | FASNMAPK14 | |
| SCHEMBL18924393 | 0.70 | FASN (0.51) | EGLN1POLBFASNHTR2CKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3010916-B1 | 1,3-DIAMINOCYCLOPENTANE CARBOXAMIDE DERIVATIVES | MERCK PATENT GMBH (DE) | 2017-09-27 | — | — | EP | disclosed |
| US-9670142-B2 | 1,3-diaminocyclopentane carboxamide derivatives | MERCK PATENT GMBH (DE) | 2017-06-06 | — | — | US | disclosed |