Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 4/20 | 0.45 |
| ▸ | HTR2C | P28335 | 3/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.45 |
| ▸ | FASN | P49327 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.40 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 2/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.38 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.38 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.38 |
| ▸ | MLNR | O43193 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19391174 | 0.89 | POLB (0.44) | MCHR1HTR2CKCNH2FASNPOLB | |
| SCHEMBL16323965 | 0.83 | FASN (0.69) | FASN | |
| SCHEMBL22259664 | 0.81 | FASN (0.53) | MCHR1HTR2CKCNH2FASN | |
| SCHEMBL18924393 | 0.81 | FASN (0.51) | MCHR1HTR2CKCNH2FASNPOLB | |
| SCHEMBL18924576 | 0.77 | EGLN1 (0.41) | MCHR1HTR2CKCNH2FASNPOLB | |
| SCHEMBL18924392 | 0.76 | MAPK14 (0.44) | POLBMAPK14NPC1RAB9AHPGD | |
| SCHEMBL18924549 | 0.75 | FASN (0.70) | MCHR1HTR2CKCNH2FASNPOLB | |
| SCHEMBL19391173 | 0.75 | FASN (0.48) | MCHR1HTR2CKCNH2FASNPOLB | |
| SCHEMBL18924390 | 0.72 | SLC6A4 (0.47) | FASNPOLBMAPK14EGLN1NPC1 | |
| SCHEMBL18924540 | 0.70 | MAPK14 (0.47) | MCHR1HTR2CKCNH2POLBMAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9670142-B2 | 1,3-diaminocyclopentane carboxamide derivatives | MERCK PATENT GMBH (DE) | 2017-06-06 | — | — | US | disclosed |