Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 1/20 | 0.47 |
| ▸ | FEN1 | P39748 | 3/20 | 0.45 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.42 |
| ▸ | FASN | P49327 | 4/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | TAF1 | P21675 | 1/20 | 0.40 |
| ▸ | CECR2 | Q9BXF3 | 1/20 | 0.40 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.40 |
| ▸ | WDR5 | P61964 | 2/20 | 0.39 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.39 |
| ▸ | GHSR | Q92847 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18924455 | 0.88 | MAPK14 (0.43) | MAPK14POLBNPC1RAB9APDK2 | |
| SCHEMBL10762514 | 0.85 | RAB9A (0.52) | POLBNPC1RAB9ABRD4CNR2 | |
| SCHEMBL18924399 | 0.85 | MAPK14 (0.51) | MAPK14POLBNPC1RAB9APDK2 | |
| SCHEMBL20897035 | 0.84 | RAB9A (0.54) | POLBNPC1RAB9ABRD4CNR2 | |
| SCHEMBL16323788 | 0.82 | FASN (0.62) | FASN | |
| SCHEMBL18924459 | 0.82 | FASN (0.56) | MAPK14FEN1ALOX5APNPC1PDK2 | |
| SCHEMBL18924393 | 0.80 | FASN (0.51) | POLBNPC1RAB9AARFASN | |
| SCHEMBL19391081 | 0.80 | ABL1 (0.45) | POLBNPC1RAB9AFASNBRD4 | |
| SCHEMBL18924475 | 0.78 | FASN (0.47) | FASN | |
| SCHEMBL18924350 | 0.78 | FASN (0.44) | NPC1FASNGHSRCNR2SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9670142-B2 | 1,3-diaminocyclopentane carboxamide derivatives | MERCK PATENT GMBH (DE) | 2017-06-06 | — | — | US | disclosed |