Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 5/20 | 0.50 |
| ▸ | RXRB | P28702 | 5/20 | 0.50 |
| ▸ | RXRG | P48443 | 5/20 | 0.50 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.47 |
| ▸ | MRGPRX4 | Q96LA9 | 5/20 | 0.47 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.45 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.45 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.45 |
| ▸ | CTSS | P25774 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18898464 | 0.83 | KMT2A (0.49) | MAPTMAPK1TDP1L3MBTL1FFAR4 | |
| SCHEMBL79415 | 0.82 | RXRA (0.52) | RXRARXRBRXRGS1PR1MRGPRX4 | |
| SCHEMBL79041 | 0.82 | RXRA (0.56) | RXRARXRBRXRGS1PR1MRGPRX4 | |
| SCHEMBL14453588 | 0.81 | MRGPRX4 (0.50) | RXRARXRBRXRGS1PR1MRGPRX4 | |
| SCHEMBL656838 | 0.81 | MRGPRX4 (0.50) | RXRARXRBRXRGS1PR1MRGPRX4 | |
| SCHEMBL24037766 | 0.81 | S1PR1 (0.50) | RXRARXRBRXRGS1PR1CTSS | |
| SCHEMBL6812974 | 0.80 | CYP4F2 (0.54) | RXRARXRBRXRGS1PR1MRGPRX4 | |
| SCHEMBL20756090 | 0.80 | RXRA (0.54) | RXRARXRBRXRGMRGPRX4CTSS | |
| SCHEMBL86405 | 0.79 | RXRA (0.49) | RXRARXRBRXRGS1PR1MRGPRX4 | |
| SCHEMBL24037767 | 0.79 | IDO1 (0.39) | RXRARXRBRXRGS1PR1MRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9670172-B2 | Heterocyclic compounds and methods of use | MEDIVATION TECHNOLOGIES, INC. (US) | 2017-06-06 | — | — | US | disclosed |