Sugi Predict

Sugi Predict / Compounds / SCHEMBL656838

SCHEMBL656838

SCHEMBL656838

Nc1ccc(OCc2ccccc2)c(C(F)(F)F)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MRGPRX4 Q96LA9 6/20 0.50
▸ RXRA P19793 2/20 0.50
▸ RXRB P28702 2/20 0.50
▸ RXRG P48443 2/20 0.50
▸ MAOB P27338 4/20 0.49
▸ GAA P10253 2/20 0.49
▸ MAPT P10636 1/20 0.49
▸ MAOA P21397 1/20 0.49
▸ RAB9A P51151 1/20 0.49
▸ SMN1; SMN2 Q16637 1/20 0.49
▸ L3MBTL1 Q9Y468 1/20 0.49
▸ CYP19A1 P11511 2/20 0.46
▸ CYP11B1 P15538 1/20 0.46
▸ CYP11B2 P19099 1/20 0.46
▸ CTSS P25774 1/20 0.45
▸ GLA P06280 1/20 0.44
▸ POLB P06746 1/20 0.44
▸ TSHR P16473 1/20 0.44
▸ HTR2C P28335 1/20 0.44
▸ SLC6A4 P31645 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL544134 0.88 MRGPRX4 (0.50) MRGPRX4RXRARXRBRXRGMAOB
SCHEMBL16046595 0.87 S1PR1 (0.41) MRGPRX4RXRARXRBRXRGMAOB
SCHEMBL30354958 0.86 MAOB (0.60) MRGPRX4RXRARXRBRXRGMAOB
SCHEMBL21340752 0.85 MAOB (0.58) MRGPRX4MAOBMAPT
SCHEMBL30354863 0.85 RXRA (0.48) MRGPRX4RXRARXRBRXRGMAOB
SCHEMBL30354795 0.85 NPC1 (0.51) MRGPRX4MAOBGAAMAOARAB9A
Hydrochloric Acid SCHEMBL11016682 0.84 NPC1 (0.50) MAOBGAAMAOARAB9ACYP19A1
SCHEMBL20756090 0.83 RXRA (0.54) MRGPRX4RXRARXRBRXRGMAPT
SCHEMBL27532762 0.83 CYP19A1 (0.48) MRGPRX4RXRARXRBRXRGMAOB
SCHEMBL3726426 0.81 PTGER1 (0.54) MRGPRX4RXRARXRBRXRGMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 154 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109705799-B YASI epoxy organic imide silica gel and preparation method thereof 东华大学 2022-03-18 — — CN claimed
CN-114015044-A Colorless transparent polyimide resin film and preparation method thereof 山东中柔新材料有限公司 2022-02-08 — — CN claimed
CN-109852330-B 3, 5-diaminobenzoic acid type silicon-containing adhesive and preparation method thereof 东华大学 2022-01-11 — — CN claimed
CN-109735295-B Imide organic silica gel and preparation method thereof 福建省海钛智能科技有限公司 2021-12-28 — — CN claimed
CN-109852331-B 3, 5-bis (4-aminophenoxy) benzoic acid type organic silica gel and preparation method thereof 福建省海钛智能科技有限公司 2021-12-28 — — CN claimed
CN-109722212-B Imide epoxy organic silica gel and preparation method thereof 福建省海钛智能科技有限公司 2021-12-28 — — CN claimed
CN-109852340-B YASI-BDAPOFP type organic fluorosilicone adhesive and preparation method thereof 福建省海钛智能科技有限公司 2021-12-28 — — CN claimed
CN-110016138-B High-flame-retardancy polyimide film and preparation method thereof 东华大学 2021-11-09 — — CN claimed
CN-111138695-A Polyimide film and preparation method thereof 深圳先进电子材料国际创新研究院 2020-05-12 — — CN claimed
CN-110698644-A Phthalimide glycidyl ester epoxy resin and preparation method thereof 东华大学 2020-01-17 — — CN claimed
CN-110591293-A Carbon fiber cable core pultrusion resin and preparation method thereof 东华大学 2019-12-20 — — CN claimed
US-20260078092-A1 SULFONYL CARBOXAMIDE COMPOUND, THEIR DERIVATIVES, AND USES THEREOF SHAH SALIM (US) 2026-03-19 — — US disclosed
US-20230278965-A1 NOVEL CARBONOHYDRAZONOYL DICYANIDE COMPOUNDS COMPRISING 2 OR MORE ARYL OR HETEROARYL CONNECTED VIA LINKER AND USE THEREOF KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2023-09-07 — — US disclosed
EP-4169916-A1 CARBONOHYDRAZONOYL DICYANIDE COMPOUND INCLUDING AT LEAST TWO TYPES OF ARYL OR HETEROARYL LINKED BY NOVEL LINKER, AND USE THEREOF Korea Institute of Science and Technology (KR) 2023-04-26 — — EP disclosed
CN-115955968-A Carbohydrazone acyldinitrile compounds comprising at least two aryl or heteroaryl groups connected by a novel linker and uses thereof 韩国科学技术研究院 2023-04-11 — — CN disclosed
EP-0861253-A1 BICYCLIC HETEROAROMATIC COMPOUNDS AS PROTEIN TYROSINE KINASE INHIBITORS GLAXO GROUP LIMITED (GB) 1998-09-02 — — EP disclosed
EP-0782570-A1 SUBSTITUTED HETEROAROMATIC COMPOUNDS AND THEIR USE IN MEDICINE THE WELLCOME FOUNDATION LIMITED (GB) 1997-07-09 — — EP disclosed
WO-1997013771-A1 BICYCLIC HETEROAROMATIC COMPOUNDS AS PROTEIN TYROSINE KINASE INHIBITORS GLAXO GROUP LIMITED (GB) 1997-04-17 — — WO disclosed
WO-1996009294-A1 SUBSTITUTED HETEROAROMATIC COMPOUNDS AND THEIR USE IN MEDICINE THE WELLCOME FOUNDATION LIMITED (GB) 1996-03-28 — — WO disclosed
US-4166735-A Cycloalkanecarboxanilide derivative herbicides SHELL OIL COMPANY (US) 1979-09-04 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260078092-A1 SULFONYL CARBOXAMIDE COMPOUND, THEIR DERIVATIVES, AND USES THEREOF ATP2A1, ATP2A2, ATP2A3 MRGPRX4 1991/4885RXRA 3425/4885RXRB 3622/4885
US-20230278965-A1 NOVEL CARBONOHYDRAZONOYL DICYANIDE COMPOUNDS COMPRISING 2 OR MORE ARYL OR HETEROARYL CONNECTED VIA LINKER AND USE THEREOF AADAC, CBR3, MTCL3 MRGPRX4 1335/4885RXRA 2075/4885RXRB 1702/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.