Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.54 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.54 |
| ▸ | RXRA | P19793 | 3/20 | 0.53 |
| ▸ | RXRB | P28702 | 3/20 | 0.53 |
| ▸ | RXRG | P48443 | 3/20 | 0.53 |
| ▸ | MRGPRX4 | Q96LA9 | 5/20 | 0.50 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.48 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.43 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL79041 | 0.88 | RXRA (0.56) | RXRARXRBRXRGMRGPRX4S1PR1 | |
| SCHEMBL79415 | 0.82 | RXRA (0.52) | RXRARXRBRXRGMRGPRX4S1PR1 | |
| SCHEMBL360371 | 0.82 | CYP4F2 (0.63) | CYP4F2CYP4A11FFAR4FFAR1LTA4H | |
| SCHEMBL22209108 | 0.81 | FFAR4 (0.54) | RXRARXRBRXRGMRGPRX4S1PR1 | |
| SCHEMBL1895781 | 0.81 | CYP4F2 (0.58) | CYP4F2CYP4A11MRGPRX4FFAR4FFAR1 | |
| SCHEMBL18924486 | 0.80 | RXRA (0.50) | RXRARXRBRXRGMRGPRX4S1PR1 | |
| SCHEMBL22208984 | 0.80 | RXRA (0.51) | RXRARXRBRXRGMRGPRX4S1PR1 | |
| SCHEMBL20756090 | 0.80 | RXRA (0.54) | RXRARXRBRXRGMRGPRX4LTA4H | |
| SCHEMBL86405 | 0.79 | RXRA (0.49) | RXRARXRBRXRGMRGPRX4S1PR1 | |
| SCHEMBL13665597 | 0.79 | S1PR1 (0.55) | MRGPRX4S1PR1FFAR1LTA4HEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1242983-C | Phenoxyacetic acid derivatives and medicinal compositions containing the same | KISSEI PHARMACEUTICAL (JP) | 2006-02-22 | — | — | CN | disclosed |
| EP-1095932-B1 | PHENOXYACETIC ACID DERIVATIVES AND MEDICINAL COMPOSITIONS CONTAINING THE SAME | KISSEI PHARMACEUTICAL (JP) | 2004-05-19 | — | — | EP | disclosed |
| US-6538152-B1 | Obesity, hyperglycemia, urinary incontinence, intestinal or biliary calculi hypermotility, pollakiuria and depression treatment | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2003-03-25 | — | — | US | disclosed |
| CN-1308603-A | Phenoxyacetic acid derivatives and medicinal compositions containing the same | KISSEI PHARMACEUTICAL (JP) | 2001-08-15 | — | — | CN | disclosed |
| EP-1095932-A1 | PHENOXYACETIC ACID DERIVATIVES AND MEDICINAL COMPOSITIONS CONTAINING THE SAME | Kissei Pharmaceutical Co., Ltd. (JP) | 2001-05-02 | — | — | EP | disclosed |