Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 4/20 | 0.64 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | OXTR | P30559 | 2/20 | 0.44 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.42 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.42 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18924431 | 0.87 | MAPK14 (0.53) | MCHR1MAPK14KMT2AMEN1NPC1 | |
| SCHEMBL18924429 | 0.85 | MAPK14 (0.53) | MCHR1MAPK14KMT2AMEN1NPC1 | |
| SCHEMBL18924563 | 0.85 | MCHR1 (0.59) | MCHR1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL11406234 | 0.82 | KMT2A (0.64) | MCHR1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL10454995 | 0.82 | KMT2A (0.64) | MCHR1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL16322802 | 0.80 | FASN (0.65) | MCHR1 | |
| SCHEMBL18924453 | 0.75 | MAPK14 (0.59) | MCHR1MAPK14KMT2AMEN1NPC1 | |
| SCHEMBL18924450 | 0.75 | MAPK14 (0.58) | MCHR1MAPK14KMT2AMEN1NPC1 | |
| SCHEMBL4085836 | 0.75 | HSD17B1 (0.64) | MCHR1KMT2AMEN1RAB9AMAPT | |
| SCHEMBL3455720 | 0.75 | SMN1; SMN2 (0.54) | KMT2AMEN1NPC1RAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9670142-B2 | 1,3-diaminocyclopentane carboxamide derivatives | MERCK PATENT GMBH (DE) | 2017-06-06 | — | — | US | disclosed |