Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | PRKCA | P17252 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4763733 | 0.82 | TSHR (0.41) | TSHRALDH1A1MMP8PRKCASMN1; SMN2 | |
| SCHEMBL12761590 | 0.80 | TSHR (0.39) | TSHRALDH1A1MMP8PRKCASMN1; SMN2 | |
| SCHEMBL23065063 | 0.78 | SMN1; SMN2 (0.40) | TSHRALDH1A1MMP8PRKCASMN1; SMN2 | |
| SCHEMBL7945587 | 0.76 | TSHR (0.46) | TSHRALDH1A1MMP8PRKCASMN1; SMN2 | |
| SCHEMBL1785988 | 0.76 | TSHR (0.46) | TSHRALDH1A1MMP8PRKCASMN1; SMN2 | |
| SCHEMBL685935 | 0.76 | PRKCA (0.55) | TSHRALDH1A1MMP8PRKCASMN1; SMN2 | |
| SCHEMBL12305438 | 0.76 | MMP8 (0.37) | TSHRALDH1A1MMP8PRKCASMN1; SMN2 | |
| SCHEMBL12310627 | 0.76 | SMN1; SMN2 (0.45) | TSHRALDH1A1MMP8PRKCASMN1; SMN2 | |
| SCHEMBL8657233 | 0.74 | TSHR (0.35) | TSHRALDH1A1MMP8PRKCASMN1; SMN2 | |
| SCHEMBL4675617 | 0.74 | TSHR (0.45) | TSHRALDH1A1MMP8PRKCASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9670200-B2 | Quaternary ammonium salt prodrugs | ALKERMES PHARMA IRELAND LIMITED (IE) | 2017-06-06 | — | — | US | disclosed |