Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | CAD | P27708 | 1/20 | 0.30 |
| ▸ | METAP2 | P50579 | 1/20 | 0.30 |
| ▸ | METAP1 | P53582 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18924778 | 0.84 | MMP8 (0.35) | MMP8ALDH1A1 | |
| SCHEMBL20260579 | 0.81 | MMP8 (0.33) | MMP8 | |
| SCHEMBL18924865 | 0.81 | MMP8 (0.33) | MMP8 | |
| SCHEMBL6895564 | 0.80 | PRKCA (0.42) | MMP8ALDH1A1ALOX15CAD | |
| SCHEMBL6893080 | 0.77 | MMP8 (0.37) | MMP8ALDH1A1ALOX15CAD | |
| SCHEMBL22267823 | 0.77 | MMP8 (0.37) | MMP8ALDH1A1ALOX15CAD | |
| SCHEMBL19359785 | 0.76 | MMP8 (0.36) | MMP8ALDH1A1 | |
| SCHEMBL20260514 | 0.75 | MMP8 (0.36) | MMP8 | |
| SCHEMBL19851975 | 0.75 | CYP4F2 (0.36) | MMP8ALDH1A1ALOX15CAD | |
| SCHEMBL19359786 | 0.74 | MMP8 (0.38) | MMP8ALDH1A1CADMETAP2METAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9670200-B2 | Quaternary ammonium salt prodrugs | ALKERMES PHARMA IRELAND LIMITED (IE) | 2017-06-06 | — | — | US | disclosed |