Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 5/20 | 0.58 |
| ▸ | CTSL | P07711 | 2/20 | 0.58 |
| ▸ | CTSB | P07858 | 2/20 | 0.58 |
| ▸ | CTSS | P25774 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | TACR1 | P25103 | 3/20 | 0.56 |
| ▸ | TYR | P14679 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6898524 | 0.89 | TACR1 (0.62) | CTSKCTSLCTSBCTSSALDH1A1 | |
| SCHEMBL15080871 | 0.89 | TACR1 (0.68) | CTSKCTSLCTSBCTSSALDH1A1 | |
| SCHEMBL6440663 | 0.86 | CTSL (0.64) | CTSKCTSLCTSBCTSSALDH1A1 | |
| SCHEMBL6440666 | 0.86 | CTSL (0.64) | CTSKCTSLCTSBCTSSALDH1A1 | |
| SCHEMBL13968379 | 0.86 | ALDH1A1 (0.62) | CTSKCTSLCTSBCTSSALDH1A1 | |
| SCHEMBL10087930 | 0.84 | CTSK (0.58) | CTSKCTSLCTSBCTSSALDH1A1 | |
| SCHEMBL30343691 | 0.83 | CTSL (0.64) | CTSKCTSLCTSBCTSSALDH1A1 | |
| SCHEMBL3065366 | 0.83 | CTSL (0.64) | CTSKCTSLCTSBCTSSALDH1A1 | |
| SCHEMBL8668091 | 0.83 | TACR1 (0.70) | CTSKCTSLCTSBCTSSTACR1 | |
| SCHEMBL7151822 | 0.83 | ALDH1A1 (0.74) | CTSKCTSLCTSBCTSSALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9670200-B2 | Quaternary ammonium salt prodrugs | ALKERMES PHARMA IRELAND LIMITED (IE) | 2017-06-06 | — | — | US | disclosed |