Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 1/20 | 0.39 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.39 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.39 |
| ▸ | HTR3B | O95264 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
| ▸ | HTR3A | P46098 | 1/20 | 0.39 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.39 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.39 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | UBE2M | P61081 | 1/20 | 0.37 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.37 |
| ▸ | WNT3A | P56704 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6886595 | 0.80 | HTR3A (0.60) | DDB1CRBNHTR3EHTR3BCHRM4 | |
| SCHEMBL30900415 | 0.75 | HCN1 (0.42) | DDB1CRBNWNT3AGBA1GAA | |
| SCHEMBL30900388 | 0.72 | CHRM3 (0.36) | DDB1CRBNUBE2MDCUN1D1WNT3A | |
| SCHEMBL20047657 | 0.68 | GAA (0.45) | DDB1CRBNUBE2MDCUN1D1GBA1 | |
| SCHEMBL5645988 | 0.65 | GAA (0.49) | DDB1CRBNGAAEPHX2 | |
| SCHEMBL3192934 | 0.65 | EPHX2 (0.57) | DDB1CRBNGBA1GAAEPHX2 | |
| SCHEMBL30997648 | 0.65 | SLC6A2 (0.42) | HTR3EHTR3BCHRM4CHRM5HRH1 | |
| SCHEMBL5531640 | 0.63 | ABCC1 (0.59) | GAA | |
| SCHEMBL20043263 | 0.63 | GAA (0.46) | DDB1CRBNGBA1GAAEPHX2 | |
| SCHEMBL5537284 | 0.62 | ABCC1 (0.60) | UBE2MDCUN1D1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9670198-B2 | Nicotinic acetylcholine receptor modulators | ASTRAEA THERAPEUTICS, LLC (US) | 2017-06-06 | — | — | US | disclosed |