Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | SSTR4 | P31391 | 2/20 | 0.35 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.35 |
| ▸ | UBE2M | P61081 | 1/20 | 0.35 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.35 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.35 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.35 |
| ▸ | WNT3A | P56704 | 4/20 | 0.35 |
| ▸ | DRD2 | P14416 | 4/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.34 |
| ▸ | HCN1 | O60741 | 1/20 | 0.34 |
| ▸ | GBA1 | P04062 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30900415 | 0.78 | HCN1 (0.42) | SSTR4SSTR1DDB1CRBNWNT3A | |
| SCHEMBL18924894 | 0.72 | DDB1 (0.39) | SSTR4SSTR1UBE2MDCUN1D1DDB1 | |
| SCHEMBL30900381 | 0.66 | SOS1 (0.39) | CHRM3GAAMAPT | |
| SCHEMBL13011378 | 0.64 | PSIP1 (0.56) | DDB1CRBNGAA | |
| SCHEMBL5645988 | 0.63 | GAA (0.49) | DDB1CRBNGAAPOLBMAPT | |
| SCHEMBL3192934 | 0.62 | EPHX2 (0.57) | DDB1CRBNGBA1GAAPOLB | |
| SCHEMBL6235230 | 0.62 | GAA (0.45) | DDB1CRBNSLC6A3GBA1GAA | |
| SCHEMBL20043263 | 0.60 | GAA (0.46) | DDB1CRBNGBA1GAAMAPT | |
| SCHEMBL13011374 | 0.60 | KIF11 (0.47) | DDB1CRBNGAA | |
| SCHEMBL6230288 | 0.60 | GAA (0.43) | UBE2MDCUN1D1DDB1CRBNSLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117658987-A | Compounds as PLK1 inhibitors, and preparation method and application thereof | 上海深势唯思科技有限责任公司 | 2024-03-08 | — | — | CN | disclosed |