Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16769998 | 0.79 | PDE10A (0.35) | GPR119HDAC1HDAC6HDAC5OPRL1 | |
| SCHEMBL18925748 | 0.75 | FLT3 (0.32) | HDAC1HDAC6HDAC5PDE10A | |
| SCHEMBL18925719 | 0.75 | LMNA (0.32) | — | |
| SCHEMBL12523394 | 0.72 | PDE8B (0.36) | OPRL1PDE10A | |
| SCHEMBL10578378 | 0.72 | OPRL1 (0.36) | OPRL1CNR2 | |
| SCHEMBL10578389 | 0.72 | OPRL1 (0.36) | OPRL1CNR2 | |
| SCHEMBL23916745 | 0.72 | TUBB4A (0.36) | HDAC1HDAC6HDAC5 | |
| SCHEMBL18925718 | 0.72 | — | — | |
| SCHEMBL10577779 | 0.71 | OPRL1 (0.36) | OPRL1 | |
| SCHEMBL10577784 | 0.71 | OPRL1 (0.36) | OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170158697-A1 | Protein Kinase Inhibitors | PHARMASCIENCE INC. (CA) | 2017-06-08 | — | — | US | disclosed |
| US-20170158697-A1 | Protein Kinase Inhibitors | PHARMASCIENCE INC. (CA) | 2017-06-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170158697-A1 | Protein Kinase Inhibitors | TEC, LCK, SRC | GPR119 3420/4885HDAC1 948/4885HDAC6 817/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.