SCHEMBL18926702

SCHEMBL18926702

O=C(O)c1ccccc1-c1ccc(Br)c2c1oc1ccccc12

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CDC14B O60729 2/20 0.43
▸ CDC14A Q9UNH5 2/20 0.43
▸ KMT2A Q03164 2/20 0.43
▸ KDM4E B2RXH2 3/20 0.40
▸ POLB P06746 2/20 0.40
▸ ALDH1A1 P00352 1/20 0.40
▸ GLA P06280 1/20 0.40
▸ ALOX5 P09917 1/20 0.40
▸ PRNP P04156 1/20 0.39
▸ TYMS P04818 1/20 0.39
▸ MEN1 O00255 1/20 0.39
▸ THRB P10828 1/20 0.39
▸ HTT P42858 1/20 0.39
▸ RECQL P46063 1/20 0.39
▸ BLM P54132 1/20 0.39
▸ PRMT1 Q99873 1/20 0.39
▸ FOLH1 Q04609 1/20 0.38
▸ CYP3A4 P08684 1/20 0.38
▸ CYP2C9 P11712 1/20 0.38
▸ ALOX12 P18054 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18926922 0.86 SLC6A3 (0.45) CDC14BCDC14AKMT2AKDM4EALDH1A1
SCHEMBL22376432 0.81 ALOX5 (0.44) CDC14BCDC14AKMT2AKDM4EALDH1A1
SCHEMBL19585040 0.81 ALOX5 (0.55) CDC14BCDC14AALOX5
SCHEMBL18854814 0.81 ALOX5 (0.55) KDM4EPOLBALOX5CYP3A4CYP2C9
SCHEMBL24862831 0.78 CDC14B (0.40) CDC14BCDC14AKMT2AKDM4EALDH1A1
SCHEMBL25853300 0.78 CDC14B (0.43) CDC14BCDC14AKDM4EALDH1A1ALOX5
SCHEMBL18382951 0.77 CDC14B (0.52) CDC14BCDC14AKMT2AKDM4EALDH1A1
SCHEMBL30152085 0.77 CDC14B (0.52) CDC14BCDC14AKMT2AKDM4EALDH1A1
SCHEMBL18165289 0.77 ALOX5 (0.55) KMT2AKDM4EALDH1A1GLAALOX5
SCHEMBL24896118 0.76 CDC14B (0.44) CDC14BCDC14AKMT2AKDM4EALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230232650-A1 ORGANOELECTROLUMINESCENT DEVICE USING POLYCYCLIC AROMATIC COMPOUNDS SFC CO., LTD (KR) 2023-07-20 — — US disclosed
US-20230232650-A1 ORGANOELECTROLUMINESCENT DEVICE USING POLYCYCLIC AROMATIC COMPOUNDS SFC CO., LTD (KR) 2023-07-20 — — US disclosed
US-11683980-B2 Condensed fluorene derivative comprising heterocyclic ring SFC CO., LTD. (KR) 2023-06-20 — — US disclosed
US-11683980-B2 Condensed fluorene derivative comprising heterocyclic ring SFC CO., LTD. (KR) 2023-06-20 — — US disclosed
US-20230134334-A1 AMINE COMPOUND HAVING FUSED RING, AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME SFC CO., LTD (KR) 2023-05-04 — — US disclosed
US-20230134334-A1 AMINE COMPOUND HAVING FUSED RING, AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME SFC CO., LTD (KR) 2023-05-04 — — US disclosed
EP-4116297-A1 CONDENSED FLUORENE DERIVATIVE COMPRISING HETEROCYCLIC RING SFC Co., Ltd. (KR) 2023-01-11 — — EP disclosed
US-20170222155-A1 CONDENSED FLUORENE DERIVATIVE COMPRISING HETEROCYCLIC RING SFC CO., LTD. (KR) 2017-08-03 — — US disclosed
US-20170222155-A1 CONDENSED FLUORENE DERIVATIVE COMPRISING HETEROCYCLIC RING SFC CO., LTD. (KR) 2017-08-03 — — US disclosed
EP-3176158-A2 CONDENSED FLUORENE DERIVATIVE COMPRISING HETERO RING SFC Co., Ltd. (KR) 2017-06-07 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170222155-A1 CONDENSED FLUORENE DERIVATIVE COMPRISING HETEROCYCLIC RING CCNE2, INF2, AFF4 CDC14B 1760/4885CDC14A 1537/4885KMT2A 1582/4885
US-11683980-B2 Condensed fluorene derivative comprising heterocyclic ring CCNE2, INF2, AFF4 CDC14B 1760/4885CDC14A 1537/4885KMT2A 1582/4885
US-20230134334-A1 AMINE COMPOUND HAVING FUSED RING, AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME EML4, SLC18A2, TYR CDC14B 3208/4885CDC14A 3551/4885KMT2A 222/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback