Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9183881 | 0.81 | NPC1 (0.50) | KMT2AMEN1RXFP1ALDH1A1HPGD | |
| SCHEMBL9868485 | 0.80 | NPC1 (0.46) | KMT2AMEN1HSD17B10ALDH1A1HPGD | |
| SCHEMBL9187106 | 0.78 | NPC1 (0.45) | KMT2AMEN1RXFP1ALDH1A1HPGD | |
| SCHEMBL9187122 | 0.78 | NPC1 (0.39) | NPC1RAB9APOLBLMNACYP2C9 | |
| SCHEMBL9184969 | 0.77 | NPC1 (0.44) | KMT2AMEN1RXFP1ALDH1A1HPGD | |
| SCHEMBL9185990 | 0.77 | NPC1 (0.44) | KMT2AMEN1RXFP1ALDH1A1HPGD | |
| SCHEMBL6920546 | 0.77 | NPC1 (0.44) | KMT2AMEN1RXFP1ALDH1A1HPGD | |
| SCHEMBL18932568 | 0.77 | KMT2A (0.44) | KMT2AMEN1RXFP1ALDH1A1HPGD | |
| SCHEMBL30683811 | 0.76 | NPC1 (0.58) | KMT2AMEN1HSD17B10ALDH1A1HPGD | |
| SCHEMBL9186051 | 0.75 | NPC1 (0.42) | KMT2AMEN1RXFP1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10823983-B2 | UV-absorbing vinylic monomers and uses thereof | ALCON INC. (CH) | 2020-11-03 | — | — | US | disclosed |
| US-10472319-B2 | Water-soluble UV-absorbing compounds and uses thereof | NOVARTIS AG (CH) | 2019-11-12 | — | — | US | disclosed |
| US-10322993-B2 | Water-soluble UV-absorbing compounds and uses thereof | NOVARTIS AG (CH) | 2019-06-18 | — | — | US | disclosed |
| US-10254567-B2 | UV-absorbing vinylic monomers and uses thereof | NOVARTIS AG (CH) | 2019-04-09 | — | — | US | disclosed |
| WO-2017145024-A1 | UV-ABSORBING VINYLIC MONOMERS AND USES THEREOF | NOVARTIS AG (CH) | 2017-08-31 | — | — | WO | disclosed |
| US-20170242275-A1 | UV-ABSORBING VINYLIC MONOMERS AND USES THEREOF | ALCON INC. (CH) | 2017-08-24 | — | — | US | disclosed |
| US-20170242275-A1 | UV-ABSORBING VINYLIC MONOMERS AND USES THEREOF | ALCON INC. (CH) | 2017-08-24 | — | — | US | disclosed |
| US-20170158611-A1 | WATER-SOLUBLE UV-ABSORBING COMPOUNDS AND USES THEREOF | ALCON INC. (CH) | 2017-06-08 | — | — | US | disclosed |
| US-20170158611-A1 | WATER-SOLUBLE UV-ABSORBING COMPOUNDS AND USES THEREOF | ALCON INC. (CH) | 2017-06-08 | — | — | US | disclosed |
| WO-2017093835-A1 | WATER-SOLUBLE UV-ABSORBING COMPOUNDS AND USES THEREOF | NOVARTIS AG (CH) | 2017-06-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170158611-A1 | WATER-SOLUBLE UV-ABSORBING COMPOUNDS AND USES THEREOF | CRYZ, UACA, XRCC5 | KMT2A 2487/4885MEN1 1311/4885RXFP1 4274/4885 |
| US-20170242275-A1 | UV-ABSORBING VINYLIC MONOMERS AND USES THEREOF | UACA, VCL, CRYZ | KMT2A 2512/4885MEN1 667/4885RXFP1 3989/4885 |
| US-10823983-B2 | UV-absorbing vinylic monomers and uses thereof | UACA, VCL, CRYZ | KMT2A 2512/4885MEN1 667/4885RXFP1 3989/4885 |
| US-10254567-B2 | UV-absorbing vinylic monomers and uses thereof | UACA, VCL, CRYZ | KMT2A 2512/4885MEN1 667/4885RXFP1 3989/4885 |
| US-10472319-B2 | Water-soluble UV-absorbing compounds and uses thereof | CRYZ, UACA, XRCC5 | KMT2A 2487/4885MEN1 1311/4885RXFP1 4274/4885 |
| US-10322993-B2 | Water-soluble UV-absorbing compounds and uses thereof | CRYZ, UACA, XRCC5 | KMT2A 2487/4885MEN1 1311/4885RXFP1 4274/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.